S497-1259 Screening compound: 2-methoxy-5-(3-{2-[3-(2-methoxyethyl)-1,2,4-oxadiazol-5-yl]phenoxy}azetidine-1-carbonyl)pyridine

S497-1259 Screening compound: 2-methoxy-5-(3-{2-[3-(2-methoxyethyl)-1,2,4-oxadiazol-5-yl]phenoxy}azetidine-1-carbonyl)pyridine
S497-1259 Screening compound: 2-methoxy-5-(3-{2-[3-(2-methoxyethyl)-1,2,4-oxadiazol-5-yl]phenoxy}azetidine-1-carbonyl)pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound S497-1259
2-methoxy-5-(3-{2-[3-(2-methoxyethyl)-1,2,4-oxadiazol-5-yl]phenoxy}azetidine-1-carbonyl)pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S497-1259

Molecular Formula

C21H22N4O5 (C21 H22 N4 O5)

Compound Name

2-methoxy-5-(3-{2-[3-(2-methoxyethyl)-1,2,4-oxadiazol-5-yl]phenoxy}azetidine-1-carbonyl)pyridine

IUPAC name

2-methoxy-5-(3-{2-[3-(2-methoxyethyl)-124-oxadiazol-5-yl]phenoxy}azetidine-1-carbonyl)pyridine

SMILES

COCCc1noc(-c(cccc2)c2OC(C2)CN2C(c(cc2)cnc2OC)=O)n1

InChI

InChI=1S/C21H22N4O5/c1-27-10-9-18-23-20(30-24-18)16-5-3-4-6-17(16)29-15-12-25(13-15)21(26)14-7-8-19(28-2)22-11-14/h3-8,11,15H,9-10,12-13H2,1-2H3

InChI Key

FAMGVPDBCMWLRD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31960049

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.43

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.952

Distribution Coefficient, logD

1.952

Water Solubility, LogSw

-2.42

Polar Surface Area

81.025

Acid Dissociation Constant (pKa)

27.37

Base Dissociation Constant (pKb)

0.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.33

S497-1259 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with S497-1259 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S497-1259?
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What is the minimum amount of S497-1259 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S497-1259
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S497-1259
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S497-1259 available by request