S497-1473 Screening compound: 2-(3-fluorophenyl)-1-(3-{2-[3-(pyrazin-2-yl)-1,2,4-oxadiazol-5-yl]phenoxy}azetidin-1-yl)ethan-1-one

S497-1473 Screening compound: 2-(3-fluorophenyl)-1-(3-{2-[3-(pyrazin-2-yl)-1,2,4-oxadiazol-5-yl]phenoxy}azetidin-1-yl)ethan-1-one
S497-1473 Screening compound: 2-(3-fluorophenyl)-1-(3-{2-[3-(pyrazin-2-yl)-1,2,4-oxadiazol-5-yl]phenoxy}azetidin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound S497-1473
2-(3-fluorophenyl)-1-(3-{2-[3-(pyrazin-2-yl)-1,2,4-oxadiazol-5-yl]phenoxy}azetidin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S497-1473

Molecular Formula

C23H18FN5O3 (C23 H18 FN5 O3)

Compound Name

2-(3-fluorophenyl)-1-(3-{2-[3-(pyrazin-2-yl)-1,2,4-oxadiazol-5-yl]phenoxy}azetidin-1-yl)ethan-1-one

IUPAC name

2-(3-fluorophenyl)-1-(3-{2-[3-(pyrazin-2-yl)-124-oxadiazol-5-yl]phenoxy}azetidin-1-yl)ethan-1-one

SMILES

O=C(Cc1cccc(F)c1)N(C1)CC1Oc(cccc1)c1-c1nc(-c2nccnc2)no1

InChI

InChI=1S/C23H18FN5O3/c24-16-5-3-4-15(10-16)11-21(30)29-13-17(14-29)31-20-7-2-1-6-18(20)23-27-22(28-32-23)19-12-25-8-9-26-19/h1-10,12,17H,11,13-14H2

InChI Key

KLIREDJINXXDEC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32010489

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.43

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.860

Distribution Coefficient, logD

2.860

Water Solubility, LogSw

-3.20

Polar Surface Area

72.877

Acid Dissociation Constant (pKa)

17.24

Base Dissociation Constant (pKb)

2.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.39

S497-1473 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with S497-1473 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S497-1473?
Check Price and Availability of S497-1473, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S497-1473 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S497-1473
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S497-1473
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S497-1473 available by request