S538-0151 Screening compound: 4-[5-(3-phenyl-1,2,4-oxadiazol-5-yl)pyrimidin-4-yl]thiomorpholine

S538-0151 Screening compound: 4-[5-(3-phenyl-1,2,4-oxadiazol-5-yl)pyrimidin-4-yl]thiomorpholine
S538-0151 Screening compound: 4-[5-(3-phenyl-1,2,4-oxadiazol-5-yl)pyrimidin-4-yl]thiomorpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound S538-0151
4-[5-(3-phenyl-1,2,4-oxadiazol-5-yl)pyrimidin-4-yl]thiomorpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S538-0151

Molecular Formula

C16H15N5OS (C16 H15 N5 OS)

Compound Name

4-[5-(3-phenyl-1,2,4-oxadiazol-5-yl)pyrimidin-4-yl]thiomorpholine

IUPAC name

4-[5-(3-phenyl-124-oxadiazol-5-yl)pyrimidin-4-yl]thiomorpholine

SMILES

C(CSCC1)N1c1ncncc1-c1nc(-c2ccccc2)no1

InChI

InChI=1S/C16H15N5OS/c1-2-4-12(5-3-1)14-19-16(22-20-14)13-10-17-11-18-15(13)21-6-8-23-9-7-21/h1-5,10-11H,6-9H2

InChI Key

UXPNMXHJJDYFNU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29012573

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

325.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.174

Distribution Coefficient, logD

3.172

Water Solubility, LogSw

-3.11

Polar Surface Area

55.310

Acid Dissociation Constant (pKa)

22.23

Base Dissociation Constant (pKb)

4.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

S538-0151 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

BRD4 Targeted Library (4534 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • Others
  • GPCR

References: we are preparing a list of scientific research reports with S538-0151 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S538-0151?
Check Price and Availability of S538-0151, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S538-0151 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S538-0151
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S538-0151
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S538-0151 available by request