S607-0257 Screening compound: 1-(cyclopropylmethyl)-3-[1-(6-methoxypyridine-3-carbonyl)piperidin-3-yl]-1H,2H,3H-imidazo[4,5-b]pyridin-2-one

S607-0257 Screening compound: 1-(cyclopropylmethyl)-3-[1-(6-methoxypyridine-3-carbonyl)piperidin-3-yl]-1H,2H,3H-imidazo[4,5-b]pyridin-2-one
S607-0257 Screening compound: 1-(cyclopropylmethyl)-3-[1-(6-methoxypyridine-3-carbonyl)piperidin-3-yl]-1H,2H,3H-imidazo[4,5-b]pyridin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound S607-0257
1-(cyclopropylmethyl)-3-[1-(6-methoxypyridine-3-carbonyl)piperidin-3-yl]-1H,2H,3H-imidazo[4,5-b]pyridin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S607-0257

Molecular Formula

C22H25N5O3 (C22 H25 N5 O3)

Compound Name

1-(cyclopropylmethyl)-3-[1-(6-methoxypyridine-3-carbonyl)piperidin-3-yl]-1H,2H,3H-imidazo[4,5-b]pyridin-2-one

IUPAC name

1-(cyclopropylmethyl)-3-[(3S)-1-(6-methoxypyridine-3-carbonyl)piperidin-3-yl]-1H2H3H-imidazo[45-b]pyridin-2-one

SMILES

COc(cc1)ncc1C(N(CCC1)C[C@H]1N(c(nccc1)c1N1CC2CC2)C1=O)=O

InChI

InChI=1S/C22H25N5O3/c1-30-19-9-8-16(12-24-19)21(28)25-11-3-4-17(14-25)27-20-18(5-2-10-23-20)26(22(27)29)13-15-6-7-15/h2,5,8-10,12,15,17H,3-4,6-7,11,13-14H2,1H3/t17-/m0/s1

InChI Key

COTALQAEBKDAMO-KRWDZBQOSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.426

Distribution Coefficient, logD

2.426

Water Solubility, LogSw

-2.25

Polar Surface Area

60.895

Acid Dissociation Constant (pKa)

21.77

Base Dissociation Constant (pKb)

1.70

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

45.46

S607-0257 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with S607-0257 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S607-0257?
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What is the minimum amount of S607-0257 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S607-0257
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S607-0257
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S607-0257 available by request