S607-0365 Screening compound: 3-[1-(1H-indazole-3-carbonyl)piperidin-3-yl]-1-(2-methoxyethyl)-1H,2H,3H-imidazo[4,5-b]pyridin-2-one

S607-0365 Screening compound: 3-[1-(1H-indazole-3-carbonyl)piperidin-3-yl]-1-(2-methoxyethyl)-1H,2H,3H-imidazo[4,5-b]pyridin-2-one
S607-0365 Screening compound: 3-[1-(1H-indazole-3-carbonyl)piperidin-3-yl]-1-(2-methoxyethyl)-1H,2H,3H-imidazo[4,5-b]pyridin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound S607-0365
3-[1-(1H-indazole-3-carbonyl)piperidin-3-yl]-1-(2-methoxyethyl)-1H,2H,3H-imidazo[4,5-b]pyridin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S607-0365

Molecular Formula

C22H24N6O3 (C22 H24 N6 O3)

Compound Name

3-[1-(1H-indazole-3-carbonyl)piperidin-3-yl]-1-(2-methoxyethyl)-1H,2H,3H-imidazo[4,5-b]pyridin-2-one

IUPAC name

3-[(3S)-1-(1H-indazole-3-carbonyl)piperidin-3-yl]-1-(2-methoxyethyl)-1H2H3H-imidazo[45-b]pyridin-2-one

SMILES

COCCN(c1c(N2[C@@H](CCC3)CN3C(c3n[nH]c4c3cccc4)=O)nccc1)C2=O

InChI

InChI=1S/C22H24N6O3/c1-31-13-12-27-18-9-4-10-23-20(18)28(22(27)30)15-6-5-11-26(14-15)21(29)19-16-7-2-3-8-17(16)24-25-19/h2-4,7-10,15H,5-6,11-14H2,1H3,(H,24,25)/t15-/m0/s1

InChI Key

KQQLOHOZQOYFRE-HNNXBMFYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.951

Distribution Coefficient, logD

1.951

Water Solubility, LogSw

-2.38

Polar Surface Area

75.630

Acid Dissociation Constant (pKa)

14.84

Base Dissociation Constant (pKb)

0.83

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.36

S607-0365 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with S607-0365 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S607-0365?
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What is the minimum amount of S607-0365 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S607-0365
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S607-0365
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S607-0365 available by request