S624-0159 Screening compound: 2'-methyl-1-(thiophene-2-carbonyl)-2',3',4',9'-tetrahydrospiro[piperidine-4,1'-pyrido[3,4-b]indole]

S624-0159 Screening compound: 2'-methyl-1-(thiophene-2-carbonyl)-2',3',4',9'-tetrahydrospiro[piperidine-4,1'-pyrido[3,4-b]indole]
S624-0159 Screening compound: 2'-methyl-1-(thiophene-2-carbonyl)-2',3',4',9'-tetrahydrospiro[piperidine-4,1'-pyrido[3,4-b]indole] alternative view

Chemical Structure Depiction of ChemDiv screening compound S624-0159
2'-methyl-1-(thiophene-2-carbonyl)-2',3',4',9'-tetrahydrospiro[piperidine-4,1'-pyrido[3,4-b]indole]

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S624-0159

Molecular Formula

C21H23N3OS (C21 H23 N3 OS)

Compound Name

2'-methyl-1-(thiophene-2-carbonyl)-2',3',4',9'-tetrahydrospiro[piperidine-4,1'-pyrido[3,4-b]indole]

IUPAC name

2'-methyl-1-(thiophene-2-carbonyl)-2'3'4'9'-tetrahydrospiro[piperidine-41'-pyrido[34-b]indole]

SMILES

CN(CC1)C(CC2)(CCN2C(c2cccs2)=O)c2c1c(cccc1)c1[nH]2

InChI

InChI=1S/C21H23N3OS/c1-23-11-8-16-15-5-2-3-6-17(15)22-19(16)21(23)9-12-24(13-10-21)20(25)18-7-4-14-26-18/h2-7,14,22H,8-13H2,1H3

InChI Key

FOFNWWHOGFIXMW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD30464567

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

365.5

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.286

Distribution Coefficient, logD

2.226

Water Solubility, LogSw

-3.54

Polar Surface Area

30.761

Acid Dissociation Constant (pKa)

18.67

Base Dissociation Constant (pKb)

8.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

S624-0159 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Natural-Product-Based Library (3730 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Ion Channels Focused Library (26372 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Nervous system
  • Cardiovascular
Structure:
  • Pool
  • Mimetics
  • Cyclic compounds
  • Cyclic compounds
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • Epigenetic
  • PPI modulators
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with S624-0159 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S624-0159?
Check Price and Availability of S624-0159, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S624-0159 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S624-0159
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S624-0159
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S624-0159 available by request