S722-0910 Screening compound: 8-{[4-({4-[(morpholin-4-yl)methyl]phenyl}methyl)piperidin-1-yl]sulfonyl}quinoline

S722-0910 Screening compound: 8-{[4-({4-[(morpholin-4-yl)methyl]phenyl}methyl)piperidin-1-yl]sulfonyl}quinoline
S722-0910 Screening compound: 8-{[4-({4-[(morpholin-4-yl)methyl]phenyl}methyl)piperidin-1-yl]sulfonyl}quinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound S722-0910
8-{[4-({4-[(morpholin-4-yl)methyl]phenyl}methyl)piperidin-1-yl]sulfonyl}quinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S722-0910

Molecular Formula

C26H31N3O3S (C26 H31 N3 O3 S)

Compound Name

8-{[4-({4-[(morpholin-4-yl)methyl]phenyl}methyl)piperidin-1-yl]sulfonyl}quinoline

IUPAC name

8-{[4-({4-[(morpholin-4-yl)methyl]phenyl}methyl)piperidin-1-yl]sulfonyl}quinoline

SMILES

O=S(c1cccc2cccnc12)(N1CCC(Cc2ccc(CN3CCOCC3)cc2)CC1)=O

InChI

InChI=1S/C26H31N3O3S/c30-33(31,25-5-1-3-24-4-2-12-27-26(24)25)29-13-10-22(11-14-29)19-21-6-8-23(9-7-21)20-28-15-17-32-18-16-28/h1-9,12,22H,10-11,13-20H2

InChI Key

HLWGMZRJPZDKCX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31992804

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.62

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.468

Distribution Coefficient, logD

3.276

Water Solubility, LogSw

-3.35

Polar Surface Area

52.852

Acid Dissociation Constant (pKa)

25.46

Base Dissociation Constant (pKb)

7.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.31

S722-0910 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with S722-0910 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S722-0910?
Check Price and Availability of S722-0910, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S722-0910 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S722-0910
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S722-0910
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S722-0910 available by request