S725-1497 Screening compound: N-[4-(cyclopropylmethyl)-1-(thiophene-3-carbonyl)piperidin-4-yl]benzamide

S725-1497 Screening compound: N-[4-(cyclopropylmethyl)-1-(thiophene-3-carbonyl)piperidin-4-yl]benzamide
S725-1497 Screening compound: N-[4-(cyclopropylmethyl)-1-(thiophene-3-carbonyl)piperidin-4-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound S725-1497
N-[4-(cyclopropylmethyl)-1-(thiophene-3-carbonyl)piperidin-4-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S725-1497

Molecular Formula

C21H24N2O2S (C21 H24 N2 O2 S)

Compound Name

N-[4-(cyclopropylmethyl)-1-(thiophene-3-carbonyl)piperidin-4-yl]benzamide

IUPAC name

N-[4-(cyclopropylmethyl)-1-(thiophene-3-carbonyl)piperidin-4-yl]benzamide

SMILES

O=C(c1cscc1)N(CC1)CCC1(CC1CC1)NC(c1ccccc1)=O

InChI

InChI=1S/C21H24N2O2S/c24-19(17-4-2-1-3-5-17)22-21(14-16-6-7-16)9-11-23(12-10-21)20(25)18-8-13-26-15-18/h1-5,8,13,15-16H,6-7,9-12,14H2,(H,22,24)

InChI Key

JJVHKNABCBVODA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32227166

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.5

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.094

Distribution Coefficient, logD

3.094

Water Solubility, LogSw

-3.37

Polar Surface Area

42.420

Acid Dissociation Constant (pKa)

13.64

Base Dissociation Constant (pKb)

4.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.86

S725-1497 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with S725-1497 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S725-1497?
Check Price and Availability of S725-1497, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S725-1497 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S725-1497
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S725-1497
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S725-1497 available by request