S736-0293 Screening compound: (1,5-dimethyl-1H-pyrazol-3-yl)[1-(3-fluorophenyl)-3-methoxy-1,7-diazaspiro[3.5]non-7-yl]methanone

S736-0293 Screening compound: (1,5-dimethyl-1H-pyrazol-3-yl)[1-(3-fluorophenyl)-3-methoxy-1,7-diazaspiro[3.5]non-7-yl]methanone
S736-0293 Screening compound: (1,5-dimethyl-1H-pyrazol-3-yl)[1-(3-fluorophenyl)-3-methoxy-1,7-diazaspiro[3.5]non-7-yl]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound S736-0293
(1,5-dimethyl-1H-pyrazol-3-yl)[1-(3-fluorophenyl)-3-methoxy-1,7-diazaspiro[3.5]non-7-yl]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S736-0293

Molecular Formula

C20H25FN4O2 (C20 H25 FN4 O2)

Compound Name

(1,5-dimethyl-1H-pyrazol-3-yl)[1-(3-fluorophenyl)-3-methoxy-1,7-diazaspiro[3.5]non-7-yl]methanone

IUPAC name

7-(15-dimethyl-1H-pyrazole-3-carbonyl)-1-(3-fluorophenyl)-3-methoxy-17-diazaspiro[3.5]nonane

SMILES

Cc1cc(C(N(CC2)CCC2(C(C2)OC)N2c2cccc(F)c2)=O)nn1C

InChI

InChI=1S/C20H25FN4O2/c1-14-11-17(22-23(14)2)19(26)24-9-7-20(8-10-24)18(27-3)13-25(20)16-6-4-5-15(21)12-16/h4-6,11-12,18H,7-10,13H2,1-3H3/t18-/m1/s1

InChI Key

FBUKXOQUTUMXSS-GOSISDBHSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.668

Distribution Coefficient, logD

1.656

Water Solubility, LogSw

-1.88

Polar Surface Area

41.123

Acid Dissociation Constant (pKa)

26.54

Base Dissociation Constant (pKb)

5.85

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

S736-0293 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with S736-0293 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S736-0293?
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What is the minimum amount of S736-0293 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S736-0293
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S736-0293
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S736-0293 available by request