S738-1344 Screening compound: 2-[3-(5-methyl-1-propyl-1H-imidazol-2-yl)azetidine-1-carbonyl]pyrazine

S738-1344 Screening compound: 2-[3-(5-methyl-1-propyl-1H-imidazol-2-yl)azetidine-1-carbonyl]pyrazine
S738-1344 Screening compound: 2-[3-(5-methyl-1-propyl-1H-imidazol-2-yl)azetidine-1-carbonyl]pyrazine alternative view

Chemical Structure Depiction of ChemDiv screening compound S738-1344
2-[3-(5-methyl-1-propyl-1H-imidazol-2-yl)azetidine-1-carbonyl]pyrazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S738-1344

Molecular Formula

C15H19N5O (C15 H19 N5 O)

Compound Name

2-[3-(5-methyl-1-propyl-1H-imidazol-2-yl)azetidine-1-carbonyl]pyrazine

IUPAC name

2-[3-(5-methyl-1-propyl-1H-imidazol-2-yl)azetidine-1-carbonyl]pyrazine

SMILES

CCCn1c(C(C2)CN2C(c2nccnc2)=O)ncc1C

InChI

InChI=1S/C15H19N5O/c1-3-6-20-11(2)7-18-14(20)12-9-19(10-12)15(21)13-8-16-4-5-17-13/h4-5,7-8,12H,3,6,9-10H2,1-2H3

InChI Key

JULCXUPOEKAIGU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31994003

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

285.35

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.954

Distribution Coefficient, logD

0.277

Water Solubility, LogSw

-1.08

Polar Surface Area

46.813

Acid Dissociation Constant (pKa)

25.99

Base Dissociation Constant (pKb)

7.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.67

S738-1344 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with S738-1344 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S738-1344?
Check Price and Availability of S738-1344, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S738-1344 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S738-1344
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S738-1344
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S738-1344 available by request