S910-0377 Screening compound: (3-methyl-2-thienyl)[6-(morpholinomethyl)-5-oxa-2-azaspiro[3.4]oct-2-yl]methanone

S910-0377 Screening compound: (3-methyl-2-thienyl)[6-(morpholinomethyl)-5-oxa-2-azaspiro[3.4]oct-2-yl]methanone
S910-0377 Screening compound: (3-methyl-2-thienyl)[6-(morpholinomethyl)-5-oxa-2-azaspiro[3.4]oct-2-yl]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound S910-0377
(3-methyl-2-thienyl)[6-(morpholinomethyl)-5-oxa-2-azaspiro[3.4]oct-2-yl]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S910-0377

Molecular Formula

C17H24N2O3S (C17 H24 N2 O3 S)

Compound Name

(3-methyl-2-thienyl)[6-(morpholinomethyl)-5-oxa-2-azaspiro[3.4]oct-2-yl]methanone

IUPAC name

2-(3-methylthiophene-2-carbonyl)-6-[(morpholin-4-yl)methyl]-5-oxa-2-azaspiro[3.4]octane

SMILES

Cc1c(C(N(C2)CC22OC(CN3CCOCC3)CC2)=O)scc1

InChI

InChI=1S/C17H24N2O3S/c1-13-3-9-23-15(13)16(20)19-11-17(12-19)4-2-14(22-17)10-18-5-7-21-8-6-18/h3,9,14H,2,4-8,10-12H2,1H3/t14-/m0/s1

InChI Key

XOGADKGFGNSLTK-AWEZNQCLSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

336.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.652

Distribution Coefficient, logD

1.650

Water Solubility, LogSw

-2.18

Polar Surface Area

36.070

Acid Dissociation Constant (pKa)

26.09

Base Dissociation Constant (pKb)

5.03

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

70.59

S910-0377 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with S910-0377 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S910-0377?
Check Price and Availability of S910-0377, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S910-0377 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S910-0377
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S910-0377
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S910-0377 available by request