S923-0475 Screening compound: (6-hydroxy-3-pyridyl){3-[1-(methylsulfonyl)-2-piperidyl]-5,6,8,9-tetrahydro-7H-[1,2,4]triazolo[4,3-d][1,4]diazepin-7-yl}methanone
Chemical Structure Depiction of ChemDiv screening compound S923-0475
(6-hydroxy-3-pyridyl){3-[1-(methylsulfonyl)-2-piperidyl]-5,6,8,9-tetrahydro-7H-[1,2,4]triazolo[4,3-d][1,4]diazepin-7-yl}methanone
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
S923-0475
Molecular Formula
C18H24N6O4S (C18 H24 N6 O4 S)
Compound Name
(6-hydroxy-3-pyridyl){3-[1-(methylsulfonyl)-2-piperidyl]-5,6,8,9-tetrahydro-7H-[1,2,4]triazolo[4,3-d][1,4]diazepin-7-yl}methanone
IUPAC name
5-[3-(1-methanesulfonylpiperidin-2-yl)-5H6H7H8H9H-[124]triazolo[43-d][14]diazepine-7-carbonyl]pyridin-2-ol
SMILES
CS(N(CCCC1)C1c1nnc(CC2)n1CCN2C(c(cc1)cnc1O)=O)(=O)=O
InChI Key
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
420.49
Hydrogen Bond Acceptors Count
11.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
4.00
Number of Nitrogen and Oxygen Atoms
10
Partition Coefficient, logP
-0.763
Distribution Coefficient, logD
-1.012
Water Solubility, LogSw
-1.67
Polar Surface Area
100.061
Acid Dissociation Constant (pKa)
7.57
Base Dissociation Constant (pKb)
6.16
Number of Chiral Centers
1.00
Percent sp3 carbon bonding
55.56
S923-0475 in Drug Discovery
Included in Screening Libraries
PPI Helix Turn 3D-Mimetics Library (71298 compounds)
PPI Inhibitors Tripeptide Mimetics (23972 compounds)
Protein-Protein Interaction Library (218420 compounds)
Alpha-Helix Mimetics Library (25899 compounds)
Beyond the Flatland Library sp3 enriched (92988 compounds)
Peptidomimetic Library (37031 compounds)
Included in 1.7M Stock Database
- PPI modulators
- PPI modulators
- PPI modulators
- PPI modulators
- PPI modulators
- Mimetics
- Mimetics
- Mimetics
- Cyclic compounds
- Mimetics
References: we are preparing a list of scientific research reports with S923-0475 chemical compound. It will be published here after verification.
Frequently Asked Questions
Check Price and Availability of S923-0475, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)