SA23-1244 Screening compound: 3-(3-{2-[(dimethylamino)methyl]-4,4-difluoropyrrolidin-1-yl}azetidine-1-carbonyl)pyridin-2-ol

SA23-1244 Screening compound: 3-(3-{2-[(dimethylamino)methyl]-4,4-difluoropyrrolidin-1-yl}azetidine-1-carbonyl)pyridin-2-ol
SA23-1244 Screening compound: 3-(3-{2-[(dimethylamino)methyl]-4,4-difluoropyrrolidin-1-yl}azetidine-1-carbonyl)pyridin-2-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound SA23-1244
3-(3-{2-[(dimethylamino)methyl]-4,4-difluoropyrrolidin-1-yl}azetidine-1-carbonyl)pyridin-2-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA23-1244

Molecular Formula

C16H22F2N4O2 (C16 H22 F2 N4 O2)

Compound Name

3-(3-{2-[(dimethylamino)methyl]-4,4-difluoropyrrolidin-1-yl}azetidine-1-carbonyl)pyridin-2-ol

IUPAC name

3-{3-[(2S)-2-[(dimethylamino)methyl]-44-difluoropyrrolidin-1-yl]azetidine-1-carbonyl}pyridin-2-ol

SMILES

CN(C)C[C@H](CC(C1)(F)F)N1C(C1)CN1C(c(cccn1)c1O)=O

InChI

InChI=1S/C16H22F2N4O2/c1-20(2)7-11-6-16(17,18)10-22(11)12-8-21(9-12)15(24)13-4-3-5-19-14(13)23/h3-5,11-12H,6-10H2,1-2H3,(H,19,23)/t11-/m1/s1

InChI Key

OKQASFRGVPCAMG-LLVKDONJSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

340.37

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.023

Distribution Coefficient, logD

0.001

Water Solubility, LogSw

-2.02

Polar Surface Area

50.019

Acid Dissociation Constant (pKa)

8.82

Base Dissociation Constant (pKb)

5.52

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

62.50

SA23-1244 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with SA23-1244 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA23-1244?
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What is the minimum amount of SA23-1244 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA23-1244
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA23-1244
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA23-1244 available by request