SA24-0122 Screening compound: 2-{3-[4,4-difluoro-2-(methoxymethyl)pyrrolidin-1-yl]azetidine-1-carbonyl}-1H-indole

SA24-0122 Screening compound: 2-{3-[4,4-difluoro-2-(methoxymethyl)pyrrolidin-1-yl]azetidine-1-carbonyl}-1H-indole
SA24-0122 Screening compound: 2-{3-[4,4-difluoro-2-(methoxymethyl)pyrrolidin-1-yl]azetidine-1-carbonyl}-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound SA24-0122
2-{3-[4,4-difluoro-2-(methoxymethyl)pyrrolidin-1-yl]azetidine-1-carbonyl}-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA24-0122

Molecular Formula

C18H21F2N3O2 (C18 H21 F2 N3 O2)

Compound Name

2-{3-[4,4-difluoro-2-(methoxymethyl)pyrrolidin-1-yl]azetidine-1-carbonyl}-1H-indole

IUPAC name

2-{3-[(2S)-44-difluoro-2-(methoxymethyl)pyrrolidin-1-yl]azetidine-1-carbonyl}-1H-indole

SMILES

COC[C@H](CC(C1)(F)F)N1C(C1)CN1C(c1cc(cccc2)c2[nH]1)=O

InChI

InChI=1S/C18H21F2N3O2/c1-25-10-13-7-18(19,20)11-23(13)14-8-22(9-14)17(24)16-6-12-4-2-3-5-15(12)21-16/h2-6,13-14,21H,7-11H2,1H3/t13-/m1/s1

InChI Key

IBJNYCRLUNLQJF-CYBMUJFWSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

349.38

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.707

Distribution Coefficient, logD

2.706

Water Solubility, LogSw

-3.30

Polar Surface Area

37.897

Acid Dissociation Constant (pKa)

15.36

Base Dissociation Constant (pKb)

4.53

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

SA24-0122 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

CNS Targets (44014 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SA24-0122 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA24-0122?
Check Price and Availability of SA24-0122, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SA24-0122 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA24-0122
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA24-0122
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA24-0122 available by request