SA24-1222 Screening compound: {1-[1-(1-ethyl-3-methyl-1H-pyrazole-4-carbonyl)azetidin-3-yl]-4,4-difluoropyrrolidin-2-yl}methanol

SA24-1222 Screening compound: {1-[1-(1-ethyl-3-methyl-1H-pyrazole-4-carbonyl)azetidin-3-yl]-4,4-difluoropyrrolidin-2-yl}methanol
SA24-1222 Screening compound: {1-[1-(1-ethyl-3-methyl-1H-pyrazole-4-carbonyl)azetidin-3-yl]-4,4-difluoropyrrolidin-2-yl}methanol alternative view

Chemical Structure Depiction of ChemDiv screening compound SA24-1222
{1-[1-(1-ethyl-3-methyl-1H-pyrazole-4-carbonyl)azetidin-3-yl]-4,4-difluoropyrrolidin-2-yl}methanol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA24-1222

Molecular Formula

C15H22F2N4O2 (C15 H22 F2 N4 O2)

Compound Name

{1-[1-(1-ethyl-3-methyl-1H-pyrazole-4-carbonyl)azetidin-3-yl]-4,4-difluoropyrrolidin-2-yl}methanol

IUPAC name

[(2S)-1-[1-(1-ethyl-3-methyl-1H-pyrazole-4-carbonyl)azetidin-3-yl]-44-difluoropyrrolidin-2-yl]methanol

SMILES

CCn1nc(C)c(C(N(C2)CC2N(C2)[C@H](CO)CC2(F)F)=O)c1

InChI

InChI=1S/C15H22F2N4O2/c1-3-20-7-13(10(2)18-20)14(23)19-5-12(6-19)21-9-15(16,17)4-11(21)8-22/h7,11-12,22H,3-6,8-9H2,1-2H3/t11-/m1/s1

InChI Key

MCUHBLNPZIKMLE-LLVKDONJSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

328.36

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.087

Distribution Coefficient, logD

0.086

Water Solubility, LogSw

-1.01

Polar Surface Area

52.094

Acid Dissociation Constant (pKa)

15.36

Base Dissociation Constant (pKb)

4.58

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

73.33

SA24-1222 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

CNS BBB Library (22607 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with SA24-1222 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA24-1222?
Check Price and Availability of SA24-1222, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SA24-1222 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA24-1222
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA24-1222
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA24-1222 available by request