SA24-1367 Screening compound: {4,4-difluoro-1-[1-(3-fluoro-4-methoxybenzoyl)azetidin-3-yl]pyrrolidin-2-yl}methanol

SA24-1367 Screening compound: {4,4-difluoro-1-[1-(3-fluoro-4-methoxybenzoyl)azetidin-3-yl]pyrrolidin-2-yl}methanol
SA24-1367 Screening compound: {4,4-difluoro-1-[1-(3-fluoro-4-methoxybenzoyl)azetidin-3-yl]pyrrolidin-2-yl}methanol alternative view

Chemical Structure Depiction of ChemDiv screening compound SA24-1367
{4,4-difluoro-1-[1-(3-fluoro-4-methoxybenzoyl)azetidin-3-yl]pyrrolidin-2-yl}methanol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA24-1367

Molecular Formula

C16H19F3N2O3 (C16 H19 F3 N2 O3)

Compound Name

{4,4-difluoro-1-[1-(3-fluoro-4-methoxybenzoyl)azetidin-3-yl]pyrrolidin-2-yl}methanol

IUPAC name

[(2S)-44-difluoro-1-[1-(3-fluoro-4-methoxybenzoyl)azetidin-3-yl]pyrrolidin-2-yl]methanol

SMILES

COc(ccc(C(N(C1)CC1N(C1)[C@H](CO)CC1(F)F)=O)c1)c1F

InChI

InChI=1S/C16H19F3N2O3/c1-24-14-3-2-10(4-13(14)17)15(23)20-6-12(7-20)21-9-16(18,19)5-11(21)8-22/h2-4,11-12,22H,5-9H2,1H3/t11-/m0/s1

InChI Key

HLRZLPVTDRDKQN-NSHDSACASA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

344.33

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.164

Distribution Coefficient, logD

1.163

Water Solubility, LogSw

-2.06

Polar Surface Area

44.869

Acid Dissociation Constant (pKa)

15.36

Base Dissociation Constant (pKb)

4.58

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

56.25

SA24-1367 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Ion Channels Focused Library (26372 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
  • Ion Channels

References: we are preparing a list of scientific research reports with SA24-1367 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA24-1367?
Check Price and Availability of SA24-1367, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SA24-1367 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA24-1367
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA24-1367
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA24-1367 available by request