SA43-0873 Screening compound: 6-methyl-2-(4-methyl-1,3-oxazole-5-carbonyl)-7-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]-2,6-diazaspiro[3.4]octane

SA43-0873 Screening compound: 6-methyl-2-(4-methyl-1,3-oxazole-5-carbonyl)-7-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]-2,6-diazaspiro[3.4]octane
SA43-0873 Screening compound: 6-methyl-2-(4-methyl-1,3-oxazole-5-carbonyl)-7-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]-2,6-diazaspiro[3.4]octane alternative view

Chemical Structure Depiction of ChemDiv screening compound SA43-0873
6-methyl-2-(4-methyl-1,3-oxazole-5-carbonyl)-7-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]-2,6-diazaspiro[3.4]octane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA43-0873

Molecular Formula

C19H20N6O3 (C19 H20 N6 O3)

Compound Name

6-methyl-2-(4-methyl-1,3-oxazole-5-carbonyl)-7-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]-2,6-diazaspiro[3.4]octane

IUPAC name

6-methyl-2-(4-methyl-13-oxazole-5-carbonyl)-7-[3-(pyridin-4-yl)-124-oxadiazol-5-yl]-26-diazaspiro[3.4]octane

SMILES

Cc1c(C(N(C2)CC2(C2)CN(C)C2c2nc(-c3ccncc3)no2)=O)ocn1

InChI

InChI=1S/C19H20N6O3/c1-12-15(27-11-21-12)18(26)25-9-19(10-25)7-14(24(2)8-19)17-22-16(23-28-17)13-3-5-20-6-4-13/h3-6,11,14H,7-10H2,1-2H3/t14-/m1/s1

InChI Key

AWKZFMOOWKAIKV-CQSZACIVSA-N

MDL Number (MFCD)

MFCD32236727

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.41

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.045

Distribution Coefficient, logD

0.385

Water Solubility, LogSw

-1.41

Polar Surface Area

80.440

Acid Dissociation Constant (pKa)

28.21

Base Dissociation Constant (pKb)

7.95

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.10

SA43-0873 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with SA43-0873 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA43-0873?
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What is the minimum amount of SA43-0873 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA43-0873
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA43-0873
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA43-0873 available by request