SA43-1023 Screening compound: 2-(3,5-dimethyl-1,2-oxazole-4-carbonyl)-6-methyl-7-[3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl]-2,6-diazaspiro[3.4]octane

SA43-1023 Screening compound: 2-(3,5-dimethyl-1,2-oxazole-4-carbonyl)-6-methyl-7-[3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl]-2,6-diazaspiro[3.4]octane
SA43-1023 Screening compound: 2-(3,5-dimethyl-1,2-oxazole-4-carbonyl)-6-methyl-7-[3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl]-2,6-diazaspiro[3.4]octane alternative view

Chemical Structure Depiction of ChemDiv screening compound SA43-1023
2-(3,5-dimethyl-1,2-oxazole-4-carbonyl)-6-methyl-7-[3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl]-2,6-diazaspiro[3.4]octane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA43-1023

Molecular Formula

C20H22N6O3 (C20 H22 N6 O3)

Compound Name

2-(3,5-dimethyl-1,2-oxazole-4-carbonyl)-6-methyl-7-[3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl]-2,6-diazaspiro[3.4]octane

IUPAC name

2-(35-dimethyl-12-oxazole-4-carbonyl)-6-methyl-7-[3-(pyridin-3-yl)-124-oxadiazol-5-yl]-26-diazaspiro[3.4]octane

SMILES

Cc1noc(C)c1C(N(C1)CC1(C1)CN(C)C1c1nc(-c2cnccc2)no1)=O

InChI

InChI=1S/C20H22N6O3/c1-12-16(13(2)28-23-12)19(27)26-10-20(11-26)7-15(25(3)9-20)18-22-17(24-29-18)14-5-4-6-21-8-14/h4-6,8,15H,7,9-11H2,1-3H3/t15-/m1/s1

InChI Key

HPSNLNZBVMNCBZ-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD32237522

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.43

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.141

Distribution Coefficient, logD

0.481

Water Solubility, LogSw

-1.15

Polar Surface Area

83.653

Acid Dissociation Constant (pKa)

27.39

Base Dissociation Constant (pKb)

7.95

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

45.00

SA43-1023 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with SA43-1023 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA43-1023?
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What is the minimum amount of SA43-1023 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA43-1023
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA43-1023
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA43-1023 available by request