SA65-1478 Screening compound: 3-{2-[1-(2,5-difluorobenzoyl)piperidin-4-yl]ethyl}-N,N-dimethyl-1,2,4-oxadiazol-5-amine

SA65-1478 Screening compound: 3-{2-[1-(2,5-difluorobenzoyl)piperidin-4-yl]ethyl}-N,N-dimethyl-1,2,4-oxadiazol-5-amine
SA65-1478 Screening compound: 3-{2-[1-(2,5-difluorobenzoyl)piperidin-4-yl]ethyl}-N,N-dimethyl-1,2,4-oxadiazol-5-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound SA65-1478
3-{2-[1-(2,5-difluorobenzoyl)piperidin-4-yl]ethyl}-N,N-dimethyl-1,2,4-oxadiazol-5-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA65-1478

Molecular Formula

C18H22F2N4O2 (C18 H22 F2 N4 O2)

Compound Name

3-{2-[1-(2,5-difluorobenzoyl)piperidin-4-yl]ethyl}-N,N-dimethyl-1,2,4-oxadiazol-5-amine

IUPAC name

3-{2-[1-(25-difluorobenzoyl)piperidin-4-yl]ethyl}-NN-dimethyl-124-oxadiazol-5-amine

SMILES

CN(C)c1nc(CCC(CC2)CCN2C(c(cc(cc2)F)c2F)=O)no1

InChI

InChI=1S/C18H22F2N4O2/c1-23(2)18-21-16(22-26-18)6-3-12-7-9-24(10-8-12)17(25)14-11-13(19)4-5-15(14)20/h4-5,11-12H,3,6-10H2,1-2H3

InChI Key

QNWUNMMROUZVEV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32002470

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

364.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.924

Distribution Coefficient, logD

2.924

Water Solubility, LogSw

-3.28

Polar Surface Area

52.431

Acid Dissociation Constant (pKa)

25.88

Base Dissociation Constant (pKb)

3.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

SA65-1478 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SA65-1478 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA65-1478?
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What is the minimum amount of SA65-1478 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA65-1478
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA65-1478
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA65-1478 available by request