SA70-1018 Screening compound: 3-{3-[1-(1,5-dimethyl-1H-pyrazole-3-carbonyl)-3-(2-methoxyethyl)piperidin-3-yl]-1,2,4-oxadiazol-5-yl}pyridine

SA70-1018 Screening compound: 3-{3-[1-(1,5-dimethyl-1H-pyrazole-3-carbonyl)-3-(2-methoxyethyl)piperidin-3-yl]-1,2,4-oxadiazol-5-yl}pyridine
SA70-1018 Screening compound: 3-{3-[1-(1,5-dimethyl-1H-pyrazole-3-carbonyl)-3-(2-methoxyethyl)piperidin-3-yl]-1,2,4-oxadiazol-5-yl}pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound SA70-1018
3-{3-[1-(1,5-dimethyl-1H-pyrazole-3-carbonyl)-3-(2-methoxyethyl)piperidin-3-yl]-1,2,4-oxadiazol-5-yl}pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA70-1018

Molecular Formula

C21H26N6O3 (C21 H26 N6 O3)

Compound Name

3-{3-[1-(1,5-dimethyl-1H-pyrazole-3-carbonyl)-3-(2-methoxyethyl)piperidin-3-yl]-1,2,4-oxadiazol-5-yl}pyridine

IUPAC name

3-{3-[1-(15-dimethyl-1H-pyrazole-3-carbonyl)-3-(2-methoxyethyl)piperidin-3-yl]-124-oxadiazol-5-yl}pyridine

SMILES

Cc1cc(C(N(CCC2)CC2(CCOC)c2noc(-c3cnccc3)n2)=O)nn1C

InChI

InChI=1S/C21H26N6O3/c1-15-12-17(24-26(15)2)19(28)27-10-5-7-21(14-27,8-11-29-3)20-23-18(30-25-20)16-6-4-9-22-13-16/h4,6,9,12-13H,5,7-8,10-11,14H2,1-3H3/t21-/m1/s1

InChI Key

QRKAQTIHBWRXGV-OAQYLSRUSA-N

MDL Number (MFCD)

MFCD32239770

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.48

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.132

Distribution Coefficient, logD

1.038

Water Solubility, LogSw

-1.28

Polar Surface Area

80.573

Acid Dissociation Constant (pKa)

27.17

Base Dissociation Constant (pKb)

6.78

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

47.62

SA70-1018 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SA70-1018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA70-1018?
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What is the minimum amount of SA70-1018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA70-1018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA70-1018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA70-1018 available by request