SA70-1184 Screening compound: 1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-(2-methoxyethyl)-3-[5-(oxan-4-yl)-1,2,4-oxadiazol-3-yl]piperidine

SA70-1184 Screening compound: 1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-(2-methoxyethyl)-3-[5-(oxan-4-yl)-1,2,4-oxadiazol-3-yl]piperidine
SA70-1184 Screening compound: 1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-(2-methoxyethyl)-3-[5-(oxan-4-yl)-1,2,4-oxadiazol-3-yl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound SA70-1184
1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-(2-methoxyethyl)-3-[5-(oxan-4-yl)-1,2,4-oxadiazol-3-yl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA70-1184

Molecular Formula

C21H30N4O4S (C21 H30 N4 O4 S)

Compound Name

1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-3-(2-methoxyethyl)-3-[5-(oxan-4-yl)-1,2,4-oxadiazol-3-yl]piperidine

IUPAC name

1-(24-dimethyl-13-thiazole-5-carbonyl)-3-(2-methoxyethyl)-3-[5-(oxan-4-yl)-124-oxadiazol-3-yl]piperidine

SMILES

Cc1c(C(N(CCC2)CC2(CCOC)c2noc(C3CCOCC3)n2)=O)sc(C)n1

InChI

InChI=1S/C21H30N4O4S/c1-14-17(30-15(2)22-14)19(26)25-9-4-7-21(13-25,8-12-27-3)20-23-18(29-24-20)16-5-10-28-11-6-16/h16H,4-13H2,1-3H3/t21-/m1/s1

InChI Key

LEJUOZMCHIZGAE-OAQYLSRUSA-N

MDL Number (MFCD)

MFCD32241160

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.56

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.995

Distribution Coefficient, logD

2.995

Water Solubility, LogSw

-2.85

Polar Surface Area

75.058

Acid Dissociation Constant (pKa)

26.56

Base Dissociation Constant (pKb)

3.20

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

71.43

SA70-1184 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

CNS MPO Library (28609 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SA70-1184 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA70-1184?
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What is the minimum amount of SA70-1184 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA70-1184
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA70-1184
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA70-1184 available by request