SA71-1146 Screening compound: 3-cyclopentyl-1-[3-(cyclopropylmethyl)-3-[5-(pyridin-3-yl)-1,2,4-oxadiazol-3-yl]piperidin-1-yl]propan-1-one

SA71-1146 Screening compound: 3-cyclopentyl-1-[3-(cyclopropylmethyl)-3-[5-(pyridin-3-yl)-1,2,4-oxadiazol-3-yl]piperidin-1-yl]propan-1-one
SA71-1146 Screening compound: 3-cyclopentyl-1-[3-(cyclopropylmethyl)-3-[5-(pyridin-3-yl)-1,2,4-oxadiazol-3-yl]piperidin-1-yl]propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound SA71-1146
3-cyclopentyl-1-[3-(cyclopropylmethyl)-3-[5-(pyridin-3-yl)-1,2,4-oxadiazol-3-yl]piperidin-1-yl]propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA71-1146

Molecular Formula

C24H32N4O2 (C24 H32 N4 O2)

Compound Name

3-cyclopentyl-1-[3-(cyclopropylmethyl)-3-[5-(pyridin-3-yl)-1,2,4-oxadiazol-3-yl]piperidin-1-yl]propan-1-one

IUPAC name

3-cyclopentyl-1-[3-(cyclopropylmethyl)-3-[5-(pyridin-3-yl)-124-oxadiazol-3-yl]piperidin-1-yl]propan-1-one

SMILES

O=C(CCC1CCCC1)N(CCC1)CC1(CC1CC1)c1noc(-c2cnccc2)n1

InChI

InChI=1S/C24H32N4O2/c29-21(11-10-18-5-1-2-6-18)28-14-4-12-24(17-28,15-19-8-9-19)23-26-22(30-27-23)20-7-3-13-25-16-20/h3,7,13,16,18-19H,1-2,4-6,8-12,14-15,17H2/t24-/m1/s1

InChI Key

LLLVZQNNFMTGBC-XMMPIXPASA-N

MDL Number (MFCD)

MFCD32241287

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.959

Distribution Coefficient, logD

3.865

Water Solubility, LogSw

-3.87

Polar Surface Area

58.026

Acid Dissociation Constant (pKa)

24.22

Base Dissociation Constant (pKb)

6.78

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

66.67

SA71-1146 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with SA71-1146 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA71-1146?
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What is the minimum amount of SA71-1146 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA71-1146
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA71-1146
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA71-1146 available by request