SA71-1254 Screening compound: 2-{3-[3-(cyclopropylmethyl)-1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)piperidin-3-yl]-1,2,4-oxadiazol-5-yl}pyridine

SA71-1254 Screening compound: 2-{3-[3-(cyclopropylmethyl)-1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)piperidin-3-yl]-1,2,4-oxadiazol-5-yl}pyridine
SA71-1254 Screening compound: 2-{3-[3-(cyclopropylmethyl)-1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)piperidin-3-yl]-1,2,4-oxadiazol-5-yl}pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound SA71-1254
2-{3-[3-(cyclopropylmethyl)-1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)piperidin-3-yl]-1,2,4-oxadiazol-5-yl}pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA71-1254

Molecular Formula

C22H25N5O2S (C22 H25 N5 O2 S)

Compound Name

2-{3-[3-(cyclopropylmethyl)-1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)piperidin-3-yl]-1,2,4-oxadiazol-5-yl}pyridine

IUPAC name

2-{3-[3-(cyclopropylmethyl)-1-(24-dimethyl-13-thiazole-5-carbonyl)piperidin-3-yl]-124-oxadiazol-5-yl}pyridine

SMILES

Cc1c(C(N(CCC2)CC2(CC2CC2)c2noc(-c3ncccc3)n2)=O)sc(C)n1

InChI

InChI=1S/C22H25N5O2S/c1-14-18(30-15(2)24-14)20(28)27-11-5-9-22(13-27,12-16-7-8-16)21-25-19(29-26-21)17-6-3-4-10-23-17/h3-4,6,10,16H,5,7-9,11-13H2,1-2H3/t22-/m1/s1

InChI Key

RJEMDHUWZKCKQR-JOCHJYFZSA-N

MDL Number (MFCD)

MFCD32240546

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

423.54

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.565

Distribution Coefficient, logD

3.565

Water Solubility, LogSw

-3.63

Polar Surface Area

67.914

Acid Dissociation Constant (pKa)

24.89

Base Dissociation Constant (pKb)

3.20

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

SA71-1254 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SA71-1254 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA71-1254?
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What is the minimum amount of SA71-1254 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA71-1254
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA71-1254
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA71-1254 available by request