SA73-0184 Screening compound: 3-{3-[4-(cyclopropylmethyl)-1-[(pyridin-2-yl)methyl]piperidin-4-yl]-1,2,4-oxadiazol-5-yl}pyridine

SA73-0184 Screening compound: 3-{3-[4-(cyclopropylmethyl)-1-[(pyridin-2-yl)methyl]piperidin-4-yl]-1,2,4-oxadiazol-5-yl}pyridine
SA73-0184 Screening compound: 3-{3-[4-(cyclopropylmethyl)-1-[(pyridin-2-yl)methyl]piperidin-4-yl]-1,2,4-oxadiazol-5-yl}pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound SA73-0184
3-{3-[4-(cyclopropylmethyl)-1-[(pyridin-2-yl)methyl]piperidin-4-yl]-1,2,4-oxadiazol-5-yl}pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA73-0184

Molecular Formula

C22H25N5O (C22 H25 N5 O)

Compound Name

3-{3-[4-(cyclopropylmethyl)-1-[(pyridin-2-yl)methyl]piperidin-4-yl]-1,2,4-oxadiazol-5-yl}pyridine

IUPAC name

3-{3-[4-(cyclopropylmethyl)-1-[(pyridin-2-yl)methyl]piperidin-4-yl]-124-oxadiazol-5-yl}pyridine

SMILES

C(C1CC1)C1(CCN(Cc2ncccc2)CC1)c1noc(-c2cnccc2)n1

InChI

InChI=1S/C22H25N5O/c1-2-11-24-19(5-1)16-27-12-8-22(9-13-27,14-17-6-7-17)21-25-20(28-26-21)18-4-3-10-23-15-18/h1-5,10-11,15,17H,6-9,12-14,16H2

InChI Key

ZRIXAWJWLLITEW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32240800

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.960

Distribution Coefficient, logD

2.755

Water Solubility, LogSw

-2.72

Polar Surface Area

54.689

Acid Dissociation Constant (pKa)

25.20

Base Dissociation Constant (pKb)

7.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.46

SA73-0184 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SA73-0184 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA73-0184?
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What is the minimum amount of SA73-0184 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA73-0184
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA73-0184
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA73-0184 available by request