SA73-0654 Screening compound: 4-(cyclopropylmethyl)-1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-[5-(oxan-4-yl)-1,2,4-oxadiazol-3-yl]piperidine

SA73-0654 Screening compound: 4-(cyclopropylmethyl)-1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-[5-(oxan-4-yl)-1,2,4-oxadiazol-3-yl]piperidine
SA73-0654 Screening compound: 4-(cyclopropylmethyl)-1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-[5-(oxan-4-yl)-1,2,4-oxadiazol-3-yl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound SA73-0654
4-(cyclopropylmethyl)-1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-[5-(oxan-4-yl)-1,2,4-oxadiazol-3-yl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA73-0654

Molecular Formula

C22H30N4O3S (C22 H30 N4 O3 S)

Compound Name

4-(cyclopropylmethyl)-1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-[5-(oxan-4-yl)-1,2,4-oxadiazol-3-yl]piperidine

IUPAC name

4-(cyclopropylmethyl)-1-(24-dimethyl-13-thiazole-5-carbonyl)-4-[5-(oxan-4-yl)-124-oxadiazol-3-yl]piperidine

SMILES

Cc1c(C(N(CC2)CCC2(CC2CC2)c2noc(C3CCOCC3)n2)=O)sc(C)n1

InChI

InChI=1S/C22H30N4O3S/c1-14-18(30-15(2)23-14)20(27)26-9-7-22(8-10-26,13-16-3-4-16)21-24-19(29-25-21)17-5-11-28-12-6-17/h16-17H,3-13H2,1-2H3

InChI Key

DZKBXIACVSTGAQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32240911

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.57

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.985

Distribution Coefficient, logD

3.985

Water Solubility, LogSw

-3.88

Polar Surface Area

67.034

Acid Dissociation Constant (pKa)

25.20

Base Dissociation Constant (pKb)

3.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

72.73

SA73-0654 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SA73-0654 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA73-0654?
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What is the minimum amount of SA73-0654 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA73-0654
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA73-0654
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA73-0654 available by request