SA73-0845 Screening compound: 1-[4-(cyclopropylmethyl)-4-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]piperidin-1-yl]-2-(pyridin-4-yl)ethan-1-one

SA73-0845 Screening compound: 1-[4-(cyclopropylmethyl)-4-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]piperidin-1-yl]-2-(pyridin-4-yl)ethan-1-one
SA73-0845 Screening compound: 1-[4-(cyclopropylmethyl)-4-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]piperidin-1-yl]-2-(pyridin-4-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound SA73-0845
1-[4-(cyclopropylmethyl)-4-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]piperidin-1-yl]-2-(pyridin-4-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA73-0845

Molecular Formula

C24H25FN4O2 (C24 H25 FN4 O2)

Compound Name

1-[4-(cyclopropylmethyl)-4-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]piperidin-1-yl]-2-(pyridin-4-yl)ethan-1-one

IUPAC name

1-[4-(cyclopropylmethyl)-4-[5-(4-fluorophenyl)-124-oxadiazol-3-yl]piperidin-1-yl]-2-(pyridin-4-yl)ethan-1-one

SMILES

O=C(Cc1ccncc1)N(CC1)CCC1(CC1CC1)c1noc(-c(cc2)ccc2F)n1

InChI

InChI=1S/C24H25FN4O2/c25-20-5-3-19(4-6-20)22-27-23(28-31-22)24(16-18-1-2-18)9-13-29(14-10-24)21(30)15-17-7-11-26-12-8-17/h3-8,11-12,18H,1-2,9-10,13-16H2

InChI Key

RMNYADRVLPIYOW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32240274

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.641

Distribution Coefficient, logD

3.628

Water Solubility, LogSw

-3.79

Polar Surface Area

57.445

Acid Dissociation Constant (pKa)

19.03

Base Dissociation Constant (pKb)

5.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.67

SA73-0845 in Drug Discovery

Included in Screening Libraries

3CLpro Library (4801 compounds)

CORONAVIRUS Library (20774 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SA73-0845 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA73-0845?
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What is the minimum amount of SA73-0845 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA73-0845
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA73-0845
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA73-0845 available by request