SA73-1145 Screening compound: 4-{3-[4-(cyclopropylmethyl)-1-(1,3-dimethyl-1H-pyrazole-5-carbonyl)piperidin-4-yl]-1,2,4-oxadiazol-5-yl}pyridine

SA73-1145 Screening compound: 4-{3-[4-(cyclopropylmethyl)-1-(1,3-dimethyl-1H-pyrazole-5-carbonyl)piperidin-4-yl]-1,2,4-oxadiazol-5-yl}pyridine
SA73-1145 Screening compound: 4-{3-[4-(cyclopropylmethyl)-1-(1,3-dimethyl-1H-pyrazole-5-carbonyl)piperidin-4-yl]-1,2,4-oxadiazol-5-yl}pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound SA73-1145
4-{3-[4-(cyclopropylmethyl)-1-(1,3-dimethyl-1H-pyrazole-5-carbonyl)piperidin-4-yl]-1,2,4-oxadiazol-5-yl}pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA73-1145

Molecular Formula

C22H26N6O2 (C22 H26 N6 O2)

Compound Name

4-{3-[4-(cyclopropylmethyl)-1-(1,3-dimethyl-1H-pyrazole-5-carbonyl)piperidin-4-yl]-1,2,4-oxadiazol-5-yl}pyridine

IUPAC name

4-{3-[4-(cyclopropylmethyl)-1-(13-dimethyl-1H-pyrazole-5-carbonyl)piperidin-4-yl]-124-oxadiazol-5-yl}pyridine

SMILES

Cc1nn(C)c(C(N(CC2)CCC2(CC2CC2)c2noc(-c3ccncc3)n2)=O)c1

InChI

InChI=1S/C22H26N6O2/c1-15-13-18(27(2)25-15)20(29)28-11-7-22(8-12-28,14-16-3-4-16)21-24-19(30-26-21)17-5-9-23-10-6-17/h5-6,9-10,13,16H,3-4,7-8,11-12,14H2,1-2H3

InChI Key

ZJGTZTPXHNBKNL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32243239

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.097

Distribution Coefficient, logD

2.096

Water Solubility, LogSw

-2.37

Polar Surface Area

71.295

Acid Dissociation Constant (pKa)

25.20

Base Dissociation Constant (pKb)

4.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

SA73-1145 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SA73-1145 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA73-1145?
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What is the minimum amount of SA73-1145 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA73-1145
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA73-1145
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA73-1145 available by request