SB01-0186 Screening compound: 1-(1-methyl-3-{[(4-methylpyridin-2-yl)oxy]methyl}-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl)-2-(3-methylphenoxy)ethan-1-one

SB01-0186 Screening compound: 1-(1-methyl-3-{[(4-methylpyridin-2-yl)oxy]methyl}-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl)-2-(3-methylphenoxy)ethan-1-one
SB01-0186 Screening compound: 1-(1-methyl-3-{[(4-methylpyridin-2-yl)oxy]methyl}-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl)-2-(3-methylphenoxy)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound SB01-0186
1-(1-methyl-3-{[(4-methylpyridin-2-yl)oxy]methyl}-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl)-2-(3-methylphenoxy)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SB01-0186

Molecular Formula

C23H26N4O3 (C23 H26 N4 O3)

Compound Name

1-(1-methyl-3-{[(4-methylpyridin-2-yl)oxy]methyl}-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl)-2-(3-methylphenoxy)ethan-1-one

IUPAC name

1-(1-methyl-3-{[(4-methylpyridin-2-yl)oxy]methyl}-1H4H5H6H7H-pyrazolo[43-c]pyridin-5-yl)-2-(3-methylphenoxy)ethan-1-one

SMILES

Cc1cccc(OCC(N(CC2)Cc3c2n(C)nc3COc2nccc(C)c2)=O)c1

InChI

InChI=1S/C23H26N4O3/c1-16-5-4-6-18(11-16)29-15-23(28)27-10-8-21-19(13-27)20(25-26(21)3)14-30-22-12-17(2)7-9-24-22/h4-7,9,11-12H,8,10,13-15H2,1-3H3

InChI Key

SBDDRQFGEQHSMH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32243444

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.549

Distribution Coefficient, logD

2.549

Water Solubility, LogSw

-2.45

Polar Surface Area

55.209

Acid Dissociation Constant (pKa)

22.95

Base Dissociation Constant (pKb)

4.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.78

SB01-0186 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SB01-0186 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SB01-0186?
Check Price and Availability of SB01-0186, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SB01-0186 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SB01-0186
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SB01-0186
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SB01-0186 available by request