SB01-0224 Screening compound: 4-methyl-2-{[1-methyl-5-(thiophene-3-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]methoxy}pyridine

SB01-0224 Screening compound: 4-methyl-2-{[1-methyl-5-(thiophene-3-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]methoxy}pyridine
SB01-0224 Screening compound: 4-methyl-2-{[1-methyl-5-(thiophene-3-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]methoxy}pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound SB01-0224
4-methyl-2-{[1-methyl-5-(thiophene-3-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]methoxy}pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SB01-0224

Molecular Formula

C19H20N4O2S (C19 H20 N4 O2 S)

Compound Name

4-methyl-2-{[1-methyl-5-(thiophene-3-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]methoxy}pyridine

IUPAC name

4-methyl-2-{[1-methyl-5-(thiophene-3-carbonyl)-1H4H5H6H7H-pyrazolo[43-c]pyridin-3-yl]methoxy}pyridine

SMILES

Cc1cc(OCc2nn(C)c(CC3)c2CN3C(c2cscc2)=O)ncc1

InChI

InChI=1S/C19H20N4O2S/c1-13-3-6-20-18(9-13)25-11-16-15-10-23(7-4-17(15)22(2)21-16)19(24)14-5-8-26-12-14/h3,5-6,8-9,12H,4,7,10-11H2,1-2H3

InChI Key

PAKMJDMHYIFEGZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32243565

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.003

Distribution Coefficient, logD

2.002

Water Solubility, LogSw

-2.46

Polar Surface Area

49.256

Acid Dissociation Constant (pKa)

21.89

Base Dissociation Constant (pKb)

4.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.58

SB01-0224 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SB01-0224 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SB01-0224?
Check Price and Availability of SB01-0224, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SB01-0224 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SB01-0224
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SB01-0224
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SB01-0224 available by request