SB03-0386 Screening compound: N-{2-[(1-cyclopropanecarbonylpiperidin-3-yl)(oxan-4-yl)amino]ethyl}-N-methylpyridine-3-carboxamide

SB03-0386 Screening compound: N-{2-[(1-cyclopropanecarbonylpiperidin-3-yl)(oxan-4-yl)amino]ethyl}-N-methylpyridine-3-carboxamide
SB03-0386 Screening compound: N-{2-[(1-cyclopropanecarbonylpiperidin-3-yl)(oxan-4-yl)amino]ethyl}-N-methylpyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound SB03-0386
N-{2-[(1-cyclopropanecarbonylpiperidin-3-yl)(oxan-4-yl)amino]ethyl}-N-methylpyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SB03-0386

Molecular Formula

C23H34N4O3 (C23 H34 N4 O3)

Compound Name

N-{2-[(1-cyclopropanecarbonylpiperidin-3-yl)(oxan-4-yl)amino]ethyl}-N-methylpyridine-3-carboxamide

IUPAC name

N-{2-[(1-cyclopropanecarbonylpiperidin-3-yl)(oxan-4-yl)amino]ethyl}-N-methylpyridine-3-carboxamide

SMILES

CN(CCN(C1CCOCC1)C(CCC1)CN1C(C1CC1)=O)C(c1cnccc1)=O

InChI

InChI=1S/C23H34N4O3/c1-25(22(28)19-4-2-10-24-16-19)12-13-27(20-8-14-30-15-9-20)21-5-3-11-26(17-21)23(29)18-6-7-18/h2,4,10,16,18,20-21H,3,5-9,11-15,17H2,1H3/t21-/m0/s1

InChI Key

KLZVGUOMKAIMIP-NRFANRHFSA-N

MDL Number (MFCD)

MFCD32245156

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.55

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.819

Distribution Coefficient, logD

0.344

Water Solubility, LogSw

-0.45

Polar Surface Area

52.778

Acid Dissociation Constant (pKa)

22.91

Base Dissociation Constant (pKb)

7.70

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

69.57

SB03-0386 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SB03-0386 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SB03-0386?
Check Price and Availability of SB03-0386, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SB03-0386 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SB03-0386
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SB03-0386
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SB03-0386 available by request