SB11-0130 Screening compound: 4-{[4-(morpholine-4-carbonyl)-1H-1,2,3-triazol-1-yl]methyl}-1-(thiophene-2-carbonyl)piperidin-4-ol

SB11-0130 Screening compound: 4-{[4-(morpholine-4-carbonyl)-1H-1,2,3-triazol-1-yl]methyl}-1-(thiophene-2-carbonyl)piperidin-4-ol
SB11-0130 Screening compound: 4-{[4-(morpholine-4-carbonyl)-1H-1,2,3-triazol-1-yl]methyl}-1-(thiophene-2-carbonyl)piperidin-4-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound SB11-0130
4-{[4-(morpholine-4-carbonyl)-1H-1,2,3-triazol-1-yl]methyl}-1-(thiophene-2-carbonyl)piperidin-4-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SB11-0130

Molecular Formula

C18H23N5O4S (C18 H23 N5 O4 S)

Compound Name

4-{[4-(morpholine-4-carbonyl)-1H-1,2,3-triazol-1-yl]methyl}-1-(thiophene-2-carbonyl)piperidin-4-ol

IUPAC name

4-{[4-(morpholine-4-carbonyl)-1H-123-triazol-1-yl]methyl}-1-(thiophene-2-carbonyl)piperidin-4-ol

SMILES

OC(Cn1nnc(C(N2CCOCC2)=O)c1)(CC1)CCN1C(c1cccs1)=O

InChI

InChI=1S/C18H23N5O4S/c24-16(22-7-9-27-10-8-22)14-12-23(20-19-14)13-18(26)3-5-21(6-4-18)17(25)15-2-1-11-28-15/h1-2,11-12,26H,3-10,13H2

InChI Key

ZCZFDPSFCMFYEB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32245932

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.48

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

-0.313

Distribution Coefficient, logD

-0.313

Water Solubility, LogSw

-1.41

Polar Surface Area

84.548

Acid Dissociation Constant (pKa)

15.47

Base Dissociation Constant (pKb)

4.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.56

SB11-0130 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SB11-0130 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SB11-0130?
Check Price and Availability of SB11-0130, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SB11-0130 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SB11-0130
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SB11-0130
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SB11-0130 available by request