SB11-0309 Screening compound: N-(2,4-dimethoxyphenyl)-1-[(4-hydroxy-4-piperidyl)methyl]-1H-1,2,3-triazole-4-carboxamide

SB11-0309 Screening compound: N-(2,4-dimethoxyphenyl)-1-[(4-hydroxy-4-piperidyl)methyl]-1H-1,2,3-triazole-4-carboxamide
SB11-0309 Screening compound: N-(2,4-dimethoxyphenyl)-1-[(4-hydroxy-4-piperidyl)methyl]-1H-1,2,3-triazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound SB11-0309
N-(2,4-dimethoxyphenyl)-1-[(4-hydroxy-4-piperidyl)methyl]-1H-1,2,3-triazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SB11-0309

Molecular Formula

C17H23N5O4 (C17 H23 N5 O4)

Compound Name

N-(2,4-dimethoxyphenyl)-1-[(4-hydroxy-4-piperidyl)methyl]-1H-1,2,3-triazole-4-carboxamide

IUPAC name

N-(24-dimethoxyphenyl)-1-[(4-hydroxypiperidin-4-yl)methyl]-1H-123-triazole-4-carboxamide

SMILES

COc(cc1)cc(OC)c1NC(c1cn(CC2(CCNCC2)O)nn1)=O

InChI

InChI=1S/C17H23N5O4/c1-25-12-3-4-13(15(9-12)26-2)19-16(23)14-10-22(21-20-14)11-17(24)5-7-18-8-6-17/h3-4,9-10,18,24H,5-8,11H2,1-2H3,(H,19,23)

InChI Key

NQWCIMXXNNTCBO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32246542

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

361.4

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

-0.355

Distribution Coefficient, logD

-3.506

Water Solubility, LogSw

-1.85

Polar Surface Area

92.045

Acid Dissociation Constant (pKa)

9.58

Base Dissociation Constant (pKb)

10.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.06

SB11-0309 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SB11-0309 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SB11-0309?
Check Price and Availability of SB11-0309, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SB11-0309 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SB11-0309
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SB11-0309
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SB11-0309 available by request