SB11-0473 Screening compound: N-cyclopentyl-1-{[4-hydroxy-1-(tetrahydro-2H-pyran-4-ylcarbonyl)-4-piperidyl]methyl}-1H-1,2,3-triazole-4-carboxamide

SB11-0473 Screening compound: N-cyclopentyl-1-{[4-hydroxy-1-(tetrahydro-2H-pyran-4-ylcarbonyl)-4-piperidyl]methyl}-1H-1,2,3-triazole-4-carboxamide
SB11-0473 Screening compound: N-cyclopentyl-1-{[4-hydroxy-1-(tetrahydro-2H-pyran-4-ylcarbonyl)-4-piperidyl]methyl}-1H-1,2,3-triazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound SB11-0473
N-cyclopentyl-1-{[4-hydroxy-1-(tetrahydro-2H-pyran-4-ylcarbonyl)-4-piperidyl]methyl}-1H-1,2,3-triazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SB11-0473

Molecular Formula

C20H31N5O4 (C20 H31 N5 O4)

Compound Name

N-cyclopentyl-1-{[4-hydroxy-1-(tetrahydro-2H-pyran-4-ylcarbonyl)-4-piperidyl]methyl}-1H-1,2,3-triazole-4-carboxamide

IUPAC name

N-cyclopentyl-1-{[4-hydroxy-1-(oxane-4-carbonyl)piperidin-4-yl]methyl}-1H-123-triazole-4-carboxamide

SMILES

OC(Cn1nnc(C(NC2CCCC2)=O)c1)(CC1)CCN1C(C1CCOCC1)=O

InChI

InChI=1S/C20H31N5O4/c26-18(21-16-3-1-2-4-16)17-13-25(23-22-17)14-20(28)7-9-24(10-8-20)19(27)15-5-11-29-12-6-15/h13,15-16,28H,1-12,14H2,(H,21,26)

InChI Key

YUBYSWMFULTSAF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32245488

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.305

Distribution Coefficient, logD

0.305

Water Solubility, LogSw

-0.94

Polar Surface Area

91.578

Acid Dissociation Constant (pKa)

14.97

Base Dissociation Constant (pKb)

5.54

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

80.00

SB11-0473 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nucleoside Mimetics Library (2197 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Cancer
  • Immune system
Structure:
  • Mimetics
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with SB11-0473 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SB11-0473?
Check Price and Availability of SB11-0473, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SB11-0473 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SB11-0473
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SB11-0473
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SB11-0473 available by request