SB25-0908 Screening compound: 2-(4-fluorophenyl)-7-{[4-(2-pyridyl)piperazino]carbonyl}-3,5,6,7,8,9-hexahydro-4H-cyclohepta[d]pyrimidin-4-one

SB25-0908 Screening compound: 2-(4-fluorophenyl)-7-{[4-(2-pyridyl)piperazino]carbonyl}-3,5,6,7,8,9-hexahydro-4H-cyclohepta[d]pyrimidin-4-one
SB25-0908 Screening compound: 2-(4-fluorophenyl)-7-{[4-(2-pyridyl)piperazino]carbonyl}-3,5,6,7,8,9-hexahydro-4H-cyclohepta[d]pyrimidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound SB25-0908
2-(4-fluorophenyl)-7-{[4-(2-pyridyl)piperazino]carbonyl}-3,5,6,7,8,9-hexahydro-4H-cyclohepta[d]pyrimidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SB25-0908

Molecular Formula

C25H26FN5O2 (C25 H26 FN5 O2)

Compound Name

2-(4-fluorophenyl)-7-{[4-(2-pyridyl)piperazino]carbonyl}-3,5,6,7,8,9-hexahydro-4H-cyclohepta[d]pyrimidin-4-one

IUPAC name

2-(4-fluorophenyl)-7-[4-(pyridin-2-yl)piperazine-1-carbonyl]-3H4H5H6H7H8H9H-cyclohepta[d]pyrimidin-4-one

SMILES

O=C(C(CC1)CCC(N=C(c(cc2)ccc2F)N2)=C1C2=O)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C25H26FN5O2/c26-19-8-4-17(5-9-19)23-28-21-11-7-18(6-10-20(21)24(32)29-23)25(33)31-15-13-30(14-16-31)22-3-1-2-12-27-22/h1-5,8-9,12,18H,6-7,10-11,13-16H2,(H,28,29,32)/t18-/m1/s1

InChI Key

YHSNNLZICKMLNW-GOSISDBHSA-N

MDL Number (MFCD)

MFCD32247176

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.976

Distribution Coefficient, logD

1.895

Water Solubility, LogSw

-3.26

Polar Surface Area

63.613

Acid Dissociation Constant (pKa)

6.36

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.00

SB25-0908 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with SB25-0908 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SB25-0908?
Check Price and Availability of SB25-0908, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SB25-0908 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SB25-0908
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SB25-0908
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SB25-0908 available by request