SB48-0383 Screening compound: (1R,5S)-N~8~,N~8~-dimethyl-3-({1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]-4-piperidyl}oxy)-8-azabicyclo[3.2.1]octane-8-carboxamide

SB48-0383 Screening compound: (1R,5S)-N~8~,N~8~-dimethyl-3-({1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]-4-piperidyl}oxy)-8-azabicyclo[3.2.1]octane-8-carboxamide
SB48-0383 Screening compound: (1R,5S)-N~8~,N~8~-dimethyl-3-({1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]-4-piperidyl}oxy)-8-azabicyclo[3.2.1]octane-8-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound SB48-0383
(1R,5S)-N~8~,N~8~-dimethyl-3-({1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]-4-piperidyl}oxy)-8-azabicyclo[3.2.1]octane-8-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SB48-0383

Molecular Formula

C19H31N5O4S (C19 H31 N5 O4 S)

Compound Name

(1R,5S)-N~8~,N~8~-dimethyl-3-({1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]-4-piperidyl}oxy)-8-azabicyclo[3.2.1]octane-8-carboxamide

IUPAC name

(1R5S)-NN-dimethyl-3-({1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]piperidin-4-yl}oxy)-8-azabicyclo[3.2.1]octane-8-carboxamide

SMILES

CN(C)C(N([C@H](CC1)C2)[C@@H]1CC2OC(CC1)CCN1S(c1cn(C)cn1)(=O)=O)=O

InChI

InChI=1S/C19H31N5O4S/c1-21(2)19(25)24-14-4-5-15(24)11-17(10-14)28-16-6-8-23(9-7-16)29(26,27)18-12-22(3)13-20-18/h12-17H,4-11H2,1-3H3/t14-,15-/m0/s1

InChI Key

HSLJTJFQBDFICU-GJZGRUSLSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

425.55

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

-0.875

Distribution Coefficient, logD

-0.875

Water Solubility, LogSw

-1.29

Polar Surface Area

66.815

Acid Dissociation Constant (pKa)

26.34

Base Dissociation Constant (pKb)

1.15

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

78.95

SB48-0383 in Drug Discovery

Included in Screening Libraries

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with SB48-0383 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SB48-0383?
Check Price and Availability of SB48-0383, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SB48-0383 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SB48-0383
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SB48-0383
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SB48-0383 available by request