SB57-1498 Screening compound: 1-[8-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-6-(methylsulfonyl)-2,6-diazaspiro[3.4]oct-2-yl]-2-(2-fluorophenyl)-1-ethanone

SB57-1498 Screening compound: 1-[8-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-6-(methylsulfonyl)-2,6-diazaspiro[3.4]oct-2-yl]-2-(2-fluorophenyl)-1-ethanone
SB57-1498 Screening compound: 1-[8-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-6-(methylsulfonyl)-2,6-diazaspiro[3.4]oct-2-yl]-2-(2-fluorophenyl)-1-ethanone alternative view

Chemical Structure Depiction of ChemDiv screening compound SB57-1498
1-[8-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-6-(methylsulfonyl)-2,6-diazaspiro[3.4]oct-2-yl]-2-(2-fluorophenyl)-1-ethanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SB57-1498

Molecular Formula

C20H23FN4O4S (C20 H23 FN4 O4 S)

Compound Name

1-[8-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-6-(methylsulfonyl)-2,6-diazaspiro[3.4]oct-2-yl]-2-(2-fluorophenyl)-1-ethanone

IUPAC name

1-[8-(3-cyclopropyl-124-oxadiazol-5-yl)-6-methanesulfonyl-26-diazaspiro[3.4]octan-2-yl]-2-(2-fluorophenyl)ethan-1-one

SMILES

CS(N(C1)CC(C2)(CN2C(Cc(cccc2)c2F)=O)C1c1nc(C2CC2)no1)(=O)=O

InChI

InChI=1S/C20H23FN4O4S/c1-30(27,28)25-9-15(19-22-18(23-29-19)13-6-7-13)20(12-25)10-24(11-20)17(26)8-14-4-2-3-5-16(14)21/h2-5,13,15H,6-12H2,1H3/t15-/m0/s1

InChI Key

DPZDAQFPBIQBJZ-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD32248732

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.49

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.281

Distribution Coefficient, logD

2.281

Water Solubility, LogSw

-2.61

Polar Surface Area

79.922

Acid Dissociation Constant (pKa)

17.63

Base Dissociation Constant (pKb)

2.57

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

55.00

SB57-1498 in Drug Discovery

Included in Screening Libraries

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with SB57-1498 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SB57-1498?
Check Price and Availability of SB57-1498, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SB57-1498 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SB57-1498
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SB57-1498
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SB57-1498 available by request