SC25-1009 Screening compound: N-(2,4-difluorobenzyl)-3-(2-pyrazinyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide

SC25-1009 Screening compound: N-(2,4-difluorobenzyl)-3-(2-pyrazinyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide
SC25-1009 Screening compound: N-(2,4-difluorobenzyl)-3-(2-pyrazinyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound SC25-1009
N-(2,4-difluorobenzyl)-3-(2-pyrazinyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SC25-1009

Molecular Formula

C18H16F2N6O (C18 H16 F2 N6 O)

Compound Name

N-(2,4-difluorobenzyl)-3-(2-pyrazinyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide

IUPAC name

N-[(24-difluorophenyl)methyl]-3-(pyrazin-2-yl)-5H6H7H8H-[124]triazolo[43-a]pyridine-8-carboxamide

SMILES

O=C(C1c2nnc(-c3nccnc3)n2CCC1)NCc(ccc(F)c1)c1F

InChI

InChI=1S/C18H16F2N6O/c19-12-4-3-11(14(20)8-12)9-23-18(27)13-2-1-7-26-16(13)24-25-17(26)15-10-21-5-6-22-15/h3-6,8,10,13H,1-2,7,9H2,(H,23,27)/t13-/m1/s1

InChI Key

UEUAALRXLULCJS-CYBMUJFWSA-N

MDL Number (MFCD)

MFCD32257988

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

370.36

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.046

Distribution Coefficient, logD

1.046

Water Solubility, LogSw

-1.48

Polar Surface Area

66.927

Acid Dissociation Constant (pKa)

12.33

Base Dissociation Constant (pKb)

2.87

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.78

SC25-1009 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with SC25-1009 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SC25-1009?
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What is the minimum amount of SC25-1009 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SC25-1009
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SC25-1009
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SC25-1009 available by request