SC41-0177 Screening compound: (2,4-difluorophenyl){3-fluoro-3-[5-(4-pyridyl)-1,2,4-oxadiazol-3-yl]-1-pyrrolidinyl}methanone

SC41-0177 Screening compound: (2,4-difluorophenyl){3-fluoro-3-[5-(4-pyridyl)-1,2,4-oxadiazol-3-yl]-1-pyrrolidinyl}methanone
SC41-0177 Screening compound: (2,4-difluorophenyl){3-fluoro-3-[5-(4-pyridyl)-1,2,4-oxadiazol-3-yl]-1-pyrrolidinyl}methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound SC41-0177
(2,4-difluorophenyl){3-fluoro-3-[5-(4-pyridyl)-1,2,4-oxadiazol-3-yl]-1-pyrrolidinyl}methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SC41-0177

Molecular Formula

C18H13F3N4O2 (C18 H13 F3 N4 O2)

Compound Name

(2,4-difluorophenyl){3-fluoro-3-[5-(4-pyridyl)-1,2,4-oxadiazol-3-yl]-1-pyrrolidinyl}methanone

IUPAC name

4-{3-[1-(24-difluorobenzoyl)-3-fluoropyrrolidin-3-yl]-124-oxadiazol-5-yl}pyridine

SMILES

O=C(c(ccc(F)c1)c1F)N(CC1)CC1(c1noc(-c2ccncc2)n1)F

InChI

InChI=1S/C18H13F3N4O2/c19-12-1-2-13(14(20)9-12)16(26)25-8-5-18(21,10-25)17-23-15(27-24-17)11-3-6-22-7-4-11/h1-4,6-7,9H,5,8,10H2/t18-/m0/s1

InChI Key

MPDGTAJKVYYITE-SFHVURJKSA-N

MDL Number (MFCD)

MFCD32259073

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.32

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.835

Distribution Coefficient, logD

2.834

Water Solubility, LogSw

-3.06

Polar Surface Area

58.020

Acid Dissociation Constant (pKa)

26.64

Base Dissociation Constant (pKb)

4.57

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.22

SC41-0177 in Drug Discovery

Included in Screening Libraries

Ion Channels Focused Library (26372 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with SC41-0177 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SC41-0177?
Check Price and Availability of SC41-0177, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SC41-0177 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SC41-0177
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SC41-0177
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SC41-0177 available by request