SC58-0174 Screening compound: (5-chloro-2-fluorophenyl)[6-methyl-8-(5-methyl-1,3-oxazol-2-yl)-2,6-diazaspiro[3.4]oct-2-yl]methanone

SC58-0174 Screening compound: (5-chloro-2-fluorophenyl)[6-methyl-8-(5-methyl-1,3-oxazol-2-yl)-2,6-diazaspiro[3.4]oct-2-yl]methanone
SC58-0174 Screening compound: (5-chloro-2-fluorophenyl)[6-methyl-8-(5-methyl-1,3-oxazol-2-yl)-2,6-diazaspiro[3.4]oct-2-yl]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound SC58-0174
(5-chloro-2-fluorophenyl)[6-methyl-8-(5-methyl-1,3-oxazol-2-yl)-2,6-diazaspiro[3.4]oct-2-yl]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SC58-0174

Molecular Formula

C18H19ClFN3O2 (C18 H19 ClFN3 O2)

Compound Name

(5-chloro-2-fluorophenyl)[6-methyl-8-(5-methyl-1,3-oxazol-2-yl)-2,6-diazaspiro[3.4]oct-2-yl]methanone

IUPAC name

2-(5-chloro-2-fluorobenzoyl)-6-methyl-8-(5-methyl-13-oxazol-2-yl)-26-diazaspiro[3.4]octane

SMILES

Cc1cnc(C2C(C3)(CN3C(c(cc(cc3)Cl)c3F)=O)CN(C)C2)o1

InChI

InChI=1S/C18H19ClFN3O2/c1-11-6-21-16(25-11)14-7-22(2)8-18(14)9-23(10-18)17(24)13-5-12(19)3-4-15(13)20/h3-6,14H,7-10H2,1-2H3/t14-/m1/s1

InChI Key

JJYVURDKKHUIOD-CQSZACIVSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

363.82

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.551

Distribution Coefficient, logD

-1.657

Water Solubility, LogSw

-3.25

Polar Surface Area

37.860

Acid Dissociation Constant (pKa)

28.36

Base Dissociation Constant (pKb)

11.61

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.44

SC58-0174 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with SC58-0174 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SC58-0174?
Check Price and Availability of SC58-0174, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SC58-0174 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SC58-0174
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SC58-0174
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SC58-0174 available by request