SC67-1290 Screening compound: 2-(1H-indol-3-yl)-1-[8-isopropyl-4-(4-methyl-4H-1,2,4-triazol-3-yl)-2,8-diazaspiro[4.5]dec-2-yl]-1-ethanone

SC67-1290 Screening compound: 2-(1H-indol-3-yl)-1-[8-isopropyl-4-(4-methyl-4H-1,2,4-triazol-3-yl)-2,8-diazaspiro[4.5]dec-2-yl]-1-ethanone
SC67-1290 Screening compound: 2-(1H-indol-3-yl)-1-[8-isopropyl-4-(4-methyl-4H-1,2,4-triazol-3-yl)-2,8-diazaspiro[4.5]dec-2-yl]-1-ethanone alternative view

Chemical Structure Depiction of ChemDiv screening compound SC67-1290
2-(1H-indol-3-yl)-1-[8-isopropyl-4-(4-methyl-4H-1,2,4-triazol-3-yl)-2,8-diazaspiro[4.5]dec-2-yl]-1-ethanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SC67-1290

Molecular Formula

C24H32N6O (C24 H32 N6 O)

Compound Name

2-(1H-indol-3-yl)-1-[8-isopropyl-4-(4-methyl-4H-1,2,4-triazol-3-yl)-2,8-diazaspiro[4.5]dec-2-yl]-1-ethanone

IUPAC name

2-(1H-indol-3-yl)-1-[4-(4-methyl-4H-124-triazol-3-yl)-8-(propan-2-yl)-28-diazaspiro[4.5]decan-2-yl]ethan-1-one

SMILES

CC(C)N(CC1)CCC1(CN(C1)C(Cc2c[nH]c3c2cccc3)=O)C1c1nncn1C

InChI

InChI=1S/C24H32N6O/c1-17(2)29-10-8-24(9-11-29)15-30(14-20(24)23-27-26-16-28(23)3)22(31)12-18-13-25-21-7-5-4-6-19(18)21/h4-7,13,16-17,20,25H,8-12,14-15H2,1-3H3/t20-/m0/s1

InChI Key

JSFNBKWDSHKTIB-FQEVSTJZSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.56

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.966

Distribution Coefficient, logD

-0.520

Water Solubility, LogSw

-2.54

Polar Surface Area

55.160

Acid Dissociation Constant (pKa)

18.09

Base Dissociation Constant (pKb)

9.88

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

54.17

SC67-1290 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with SC67-1290 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SC67-1290?
Check Price and Availability of SC67-1290, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SC67-1290 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SC67-1290
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SC67-1290
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SC67-1290 available by request