SC74-0675 Screening compound: 3-methyl-N~2~-[(1S,2R,4R)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)-4-(1-pyrrolidinylcarbonyl)cyclopentyl]-2-pyridinecarboxamide

SC74-0675 Screening compound: 3-methyl-N~2~-[(1S,2R,4R)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)-4-(1-pyrrolidinylcarbonyl)cyclopentyl]-2-pyridinecarboxamide
SC74-0675 Screening compound: 3-methyl-N~2~-[(1S,2R,4R)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)-4-(1-pyrrolidinylcarbonyl)cyclopentyl]-2-pyridinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound SC74-0675
3-methyl-N~2~-[(1S,2R,4R)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)-4-(1-pyrrolidinylcarbonyl)cyclopentyl]-2-pyridinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SC74-0675

Molecular Formula

C25H27N5O3 (C25 H27 N5 O3)

Compound Name

3-methyl-N~2~-[(1S,2R,4R)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)-4-(1-pyrrolidinylcarbonyl)cyclopentyl]-2-pyridinecarboxamide

IUPAC name

3-methyl-N-[(1S2R4R)-2-(3-phenyl-124-oxadiazol-5-yl)-4-(pyrrolidine-1-carbonyl)cyclopentyl]pyridine-2-carboxamide

SMILES

Cc1cccnc1C(N[C@@H](C[C@@H](C1)C(N2CCCC2)=O)[C@@H]1c1nc(-c2ccccc2)no1)=O

InChI

InChI=1S/C25H27N5O3/c1-16-8-7-11-26-21(16)23(31)27-20-15-18(25(32)30-12-5-6-13-30)14-19(20)24-28-22(29-33-24)17-9-3-2-4-10-17/h2-4,7-11,18-20H,5-6,12-15H2,1H3,(H,27,31)/t18-,19+,20-/m0/s1

InChI Key

GADZNZPRVFPRNC-ZCNNSNEGSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.745

Distribution Coefficient, logD

3.745

Water Solubility, LogSw

-3.85

Polar Surface Area

83.371

Acid Dissociation Constant (pKa)

13.84

Base Dissociation Constant (pKb)

2.77

Number of Chiral Centers

3.00

Percent sp3 carbon bonding

40.00

SC74-0675 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with SC74-0675 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SC74-0675?
Check Price and Availability of SC74-0675, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SC74-0675 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SC74-0675
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SC74-0675
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SC74-0675 available by request