SC74-0778 Screening compound: 2,4-dimethyl-N~5~-[(1S,2R,4R)-4-(morpholinocarbonyl)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)cyclopentyl]-1,3-thiazole-5-carboxamide

SC74-0778 Screening compound: 2,4-dimethyl-N~5~-[(1S,2R,4R)-4-(morpholinocarbonyl)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)cyclopentyl]-1,3-thiazole-5-carboxamide
SC74-0778 Screening compound: 2,4-dimethyl-N~5~-[(1S,2R,4R)-4-(morpholinocarbonyl)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)cyclopentyl]-1,3-thiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound SC74-0778
2,4-dimethyl-N~5~-[(1S,2R,4R)-4-(morpholinocarbonyl)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)cyclopentyl]-1,3-thiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SC74-0778

Molecular Formula

C24H27N5O4S (C24 H27 N5 O4 S)

Compound Name

2,4-dimethyl-N~5~-[(1S,2R,4R)-4-(morpholinocarbonyl)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)cyclopentyl]-1,3-thiazole-5-carboxamide

IUPAC name

24-dimethyl-N-[(1S2R4R)-4-(morpholine-4-carbonyl)-2-(3-phenyl-124-oxadiazol-5-yl)cyclopentyl]-13-thiazole-5-carboxamide

SMILES

Cc1c(C(N[C@@H](C[C@@H](C2)C(N3CCOCC3)=O)[C@@H]2c2nc(-c3ccccc3)no2)=O)sc(C)n1

InChI

InChI=1S/C24H27N5O4S/c1-14-20(34-15(2)25-14)22(30)26-19-13-17(24(31)29-8-10-32-11-9-29)12-18(19)23-27-21(28-33-23)16-6-4-3-5-7-16/h3-7,17-19H,8-13H2,1-2H3,(H,26,30)/t17-,18+,19-/m0/s1

InChI Key

YFACWAQMATWONT-OTWHNJEPSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.58

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.239

Distribution Coefficient, logD

3.239

Water Solubility, LogSw

-3.39

Polar Surface Area

91.485

Acid Dissociation Constant (pKa)

14.39

Base Dissociation Constant (pKb)

2.07

Number of Chiral Centers

3.00

Percent sp3 carbon bonding

45.83

SC74-0778 in Drug Discovery

Included in Screening Libraries

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with SC74-0778 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SC74-0778?
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What is the minimum amount of SC74-0778 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SC74-0778
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SC74-0778
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SC74-0778 available by request