T138-0433 Screening compound: 3-methyl-1-[1-(2-phenylacetyl)piperidin-4-yl]-7-oxa-1,3-diazaspiro[4.4]nonan-2-one

T138-0433 Screening compound: 3-methyl-1-[1-(2-phenylacetyl)piperidin-4-yl]-7-oxa-1,3-diazaspiro[4.4]nonan-2-one
T138-0433 Screening compound: 3-methyl-1-[1-(2-phenylacetyl)piperidin-4-yl]-7-oxa-1,3-diazaspiro[4.4]nonan-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound T138-0433
3-methyl-1-[1-(2-phenylacetyl)piperidin-4-yl]-7-oxa-1,3-diazaspiro[4.4]nonan-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T138-0433

Molecular Formula

C20H27N3O3 (C20 H27 N3 O3)

Compound Name

3-methyl-1-[1-(2-phenylacetyl)piperidin-4-yl]-7-oxa-1,3-diazaspiro[4.4]nonan-2-one

IUPAC name

3-methyl-1-[1-(2-phenylacetyl)piperidin-4-yl]-7-oxa-13-diazaspiro[4.4]nonan-2-one

SMILES

CN(CC1(COCC1)N1C(CC2)CCN2C(Cc2ccccc2)=O)C1=O

InChI

InChI=1S/C20H27N3O3/c1-21-14-20(9-12-26-15-20)23(19(21)25)17-7-10-22(11-8-17)18(24)13-16-5-3-2-4-6-16/h2-6,17H,7-15H2,1H3/t20-/m0/s1

InChI Key

YDGLZSHBAVRMDR-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD31993818

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

357.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.771

Distribution Coefficient, logD

1.771

Water Solubility, LogSw

-1.91

Polar Surface Area

43.673

Acid Dissociation Constant (pKa)

18.21

Base Dissociation Constant (pKb)

2.21

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

60.00

T138-0433 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T138-0433 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T138-0433?
Check Price and Availability of T138-0433, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T138-0433 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T138-0433
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T138-0433
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T138-0433 available by request