T138-0565 Screening compound: 3-(2-methoxyethyl)-1-{1-[3-(3-methoxyphenyl)propanoyl]piperidin-4-yl}-7-oxa-1,3-diazaspiro[4.4]nonan-2-one

T138-0565 Screening compound: 3-(2-methoxyethyl)-1-{1-[3-(3-methoxyphenyl)propanoyl]piperidin-4-yl}-7-oxa-1,3-diazaspiro[4.4]nonan-2-one
T138-0565 Screening compound: 3-(2-methoxyethyl)-1-{1-[3-(3-methoxyphenyl)propanoyl]piperidin-4-yl}-7-oxa-1,3-diazaspiro[4.4]nonan-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound T138-0565
3-(2-methoxyethyl)-1-{1-[3-(3-methoxyphenyl)propanoyl]piperidin-4-yl}-7-oxa-1,3-diazaspiro[4.4]nonan-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T138-0565

Molecular Formula

C24H35N3O5 (C24 H35 N3 O5)

Compound Name

3-(2-methoxyethyl)-1-{1-[3-(3-methoxyphenyl)propanoyl]piperidin-4-yl}-7-oxa-1,3-diazaspiro[4.4]nonan-2-one

IUPAC name

3-(2-methoxyethyl)-1-{1-[3-(3-methoxyphenyl)propanoyl]piperidin-4-yl}-7-oxa-13-diazaspiro[4.4]nonan-2-one

SMILES

COCCN(CC1(COCC1)N1C(CC2)CCN2C(CCc2cc(OC)ccc2)=O)C1=O

InChI

InChI=1S/C24H35N3O5/c1-30-15-13-26-17-24(10-14-32-18-24)27(23(26)29)20-8-11-25(12-9-20)22(28)7-6-19-4-3-5-21(16-19)31-2/h3-5,16,20H,6-15,17-18H2,1-2H3/t24-/m0/s1

InChI Key

WEDVTJFIDIVWFP-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD31969348

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.56

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.205

Distribution Coefficient, logD

2.205

Water Solubility, LogSw

-2.42

Polar Surface Area

59.822

Acid Dissociation Constant (pKa)

23.24

Base Dissociation Constant (pKb)

1.97

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

66.67

T138-0565 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T138-0565 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T138-0565?
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What is the minimum amount of T138-0565 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T138-0565
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T138-0565
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T138-0565 available by request