T143-0358 Screening compound: 2-fluoro-N-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]benzamide

T143-0358 Screening compound: 2-fluoro-N-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]benzamide
T143-0358 Screening compound: 2-fluoro-N-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T143-0358
2-fluoro-N-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T143-0358

Molecular Formula

C22H22F2N4O (C22 H22 F2 N4 O)

Compound Name

2-fluoro-N-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]benzamide

IUPAC name

2-fluoro-N-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]benzamide

SMILES

Cn(c(NC(c(cccc1)c1F)=O)c1N2CCCCC2)nc1-c1cc(F)ccc1

InChI

InChI=1S/C22H22F2N4O/c1-27-21(25-22(29)17-10-3-4-11-18(17)24)20(28-12-5-2-6-13-28)19(26-27)15-8-7-9-16(23)14-15/h3-4,7-11,14H,2,5-6,12-13H2,1H3,(H,25,29)

InChI Key

YJEMUYVXQBRAAD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31994314

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

396.44

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.049

Distribution Coefficient, logD

3.935

Water Solubility, LogSw

-4.10

Polar Surface Area

40.614

Acid Dissociation Constant (pKa)

7.92

Base Dissociation Constant (pKb)

-0.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.27

T143-0358 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

New Agro Library (44492 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Agro:
  • Agro
Therapeutical areas:
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with T143-0358 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T143-0358?
Check Price and Availability of T143-0358, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T143-0358 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T143-0358
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T143-0358
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T143-0358 available by request