T157-0131 Screening compound: N-{5H,6H,7H-cyclopenta[b]pyridin-3-yl}cyclopentanecarboxamide

T157-0131 Screening compound: N-{5H,6H,7H-cyclopenta[b]pyridin-3-yl}cyclopentanecarboxamide
T157-0131 Screening compound: N-{5H,6H,7H-cyclopenta[b]pyridin-3-yl}cyclopentanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T157-0131
N-{5H,6H,7H-cyclopenta[b]pyridin-3-yl}cyclopentanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T157-0131

Molecular Formula

C14H18N2O (C14 H18 N2 O)

Compound Name

N-{5H,6H,7H-cyclopenta[b]pyridin-3-yl}cyclopentanecarboxamide

IUPAC name

N-{5H6H7H-cyclopenta[b]pyridin-3-yl}cyclopentanecarboxamide

SMILES

O=C(C1CCCC1)Nc1cnc(CCC2)c2c1

InChI

InChI=1S/C14H18N2O/c17-14(10-4-1-2-5-10)16-12-8-11-6-3-7-13(11)15-9-12/h8-10H,1-7H2,(H,16,17)

InChI Key

ZKTJBHGESWBXGQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD30463325

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

230.31

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

2.534

Distribution Coefficient, logD

2.529

Water Solubility, LogSw

-2.72

Polar Surface Area

34.813

Acid Dissociation Constant (pKa)

11.74

Base Dissociation Constant (pKb)

5.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

57.14

T157-0131 in Drug Discovery

Included in Screening Libraries

3D-Fragment Library (4274 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

CNS Targets (44014 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Fragments
  • Cyclic compounds
Therapeutical areas:
  • Nervous system
  • Nervous system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • Epigenetic
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with T157-0131 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T157-0131?
Check Price and Availability of T157-0131, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T157-0131 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T157-0131
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T157-0131
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T157-0131 available by request