T160-0164 Screening compound: 3-(4-{[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]methyl}piperidine-1-carbonyl)-2,6-dimethoxypyridine

T160-0164 Screening compound: 3-(4-{[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]methyl}piperidine-1-carbonyl)-2,6-dimethoxypyridine
T160-0164 Screening compound: 3-(4-{[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]methyl}piperidine-1-carbonyl)-2,6-dimethoxypyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound T160-0164
3-(4-{[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]methyl}piperidine-1-carbonyl)-2,6-dimethoxypyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T160-0164

Molecular Formula

C22H30N4O3 (C22 H30 N4 O3)

Compound Name

3-(4-{[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]methyl}piperidine-1-carbonyl)-2,6-dimethoxypyridine

IUPAC name

3-(4-{[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]methyl}piperidine-1-carbonyl)-26-dimethoxypyridine

SMILES

Cc1cnc(CC(CC2)CCN2C(c(ccc(OC)n2)c2OC)=O)n1CC1CC1

InChI

InChI=1S/C22H30N4O3/c1-15-13-23-19(26(15)14-17-4-5-17)12-16-8-10-25(11-9-16)22(27)18-6-7-20(28-2)24-21(18)29-3/h6-7,13,16-17H,4-5,8-12,14H2,1-3H3

InChI Key

FVICTOQALVECSI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31972926

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.731

Distribution Coefficient, logD

1.711

Water Solubility, LogSw

-3.88

Polar Surface Area

53.661

Acid Dissociation Constant (pKa)

25.02

Base Dissociation Constant (pKb)

9.41

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

59.09

T160-0164 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T160-0164 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T160-0164?
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What is the minimum amount of T160-0164 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T160-0164
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T160-0164
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T160-0164 available by request