T160-0179 Screening compound: 4-{[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]methyl}-1-(3-fluoro-4-methoxybenzoyl)piperidine

T160-0179 Screening compound: 4-{[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]methyl}-1-(3-fluoro-4-methoxybenzoyl)piperidine
T160-0179 Screening compound: 4-{[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]methyl}-1-(3-fluoro-4-methoxybenzoyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound T160-0179
4-{[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]methyl}-1-(3-fluoro-4-methoxybenzoyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T160-0179

Molecular Formula

C22H28FN3O2 (C22 H28 FN3 O2)

Compound Name

4-{[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]methyl}-1-(3-fluoro-4-methoxybenzoyl)piperidine

IUPAC name

4-{[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]methyl}-1-(3-fluoro-4-methoxybenzoyl)piperidine

SMILES

Cc1cnc(CC(CC2)CCN2C(c(cc2)cc(F)c2OC)=O)n1CC1CC1

InChI

InChI=1S/C22H28FN3O2/c1-15-13-24-21(26(15)14-17-3-4-17)11-16-7-9-25(10-8-16)22(27)18-5-6-20(28-2)19(23)12-18/h5-6,12-13,16-17H,3-4,7-11,14H2,1-2H3

InChI Key

GTRQPFFLXVGYIT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31999163

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.472

Distribution Coefficient, logD

1.453

Water Solubility, LogSw

-3.42

Polar Surface Area

36.930

Acid Dissociation Constant (pKa)

25.02

Base Dissociation Constant (pKb)

9.41

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

54.54

T160-0179 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds
Agro:
  • Agro

References: we are preparing a list of scientific research reports with T160-0179 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T160-0179?
Check Price and Availability of T160-0179, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T160-0179 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T160-0179
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T160-0179
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T160-0179 available by request