T160-0185 Screening compound: 1-(4-{[1-(CYCLOPROPYLMETHYL)-5-METHYL-1H-IMIDAZOL-2-YL]METHYL}PIPERIDIN-1-YL)-3-(4-METHOXYPHENYL)PROPAN-1-ONE

T160-0185 Screening compound: 1-(4-{[1-(CYCLOPROPYLMETHYL)-5-METHYL-1H-IMIDAZOL-2-YL]METHYL}PIPERIDIN-1-YL)-3-(4-METHOXYPHENYL)PROPAN-1-ONE
T160-0185 Screening compound: 1-(4-{[1-(CYCLOPROPYLMETHYL)-5-METHYL-1H-IMIDAZOL-2-YL]METHYL}PIPERIDIN-1-YL)-3-(4-METHOXYPHENYL)PROPAN-1-ONE alternative view

Chemical Structure Depiction of ChemDiv screening compound T160-0185
1-(4-{[1-(CYCLOPROPYLMETHYL)-5-METHYL-1H-IMIDAZOL-2-YL]METHYL}PIPERIDIN-1-YL)-3-(4-METHOXYPHENYL)PROPAN-1-ONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T160-0185

Molecular Formula

C24H33N3O2 (C24 H33 N3 O2)

Compound Name

1-(4-{[1-(CYCLOPROPYLMETHYL)-5-METHYL-1H-IMIDAZOL-2-YL]METHYL}PIPERIDIN-1-YL)-3-(4-METHOXYPHENYL)PROPAN-1-ONE

IUPAC name

1-(4-{[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]methyl}piperidin-1-yl)-3-(4-methoxyphenyl)propan-1-one

SMILES

Cc1cnc(CC(CC2)CCN2C(CCc(cc2)ccc2OC)=O)n1CC1CC1

InChI

InChI=1S/C24H33N3O2/c1-18-16-25-23(27(18)17-21-3-4-21)15-20-11-13-26(14-12-20)24(28)10-7-19-5-8-22(29-2)9-6-19/h5-6,8-9,16,20-21H,3-4,7,10-15,17H2,1-2H3

InChI Key

YFIUOWASECDOPM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31972959

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

395.55

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.016

Distribution Coefficient, logD

1.997

Water Solubility, LogSw

-4.10

Polar Surface Area

36.316

Acid Dissociation Constant (pKa)

23.24

Base Dissociation Constant (pKb)

9.41

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

58.33

T160-0185 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T160-0185 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T160-0185?
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What is the minimum amount of T160-0185 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T160-0185
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T160-0185
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T160-0185 available by request