T160-0638 Screening compound: 1-(1-ethyl-1H-pyrazole-3-carbonyl)-4-({1-[(4-fluorophenyl)methyl]-5-methyl-1H-imidazol-2-yl}methyl)piperidine

T160-0638 Screening compound: 1-(1-ethyl-1H-pyrazole-3-carbonyl)-4-({1-[(4-fluorophenyl)methyl]-5-methyl-1H-imidazol-2-yl}methyl)piperidine
T160-0638 Screening compound: 1-(1-ethyl-1H-pyrazole-3-carbonyl)-4-({1-[(4-fluorophenyl)methyl]-5-methyl-1H-imidazol-2-yl}methyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound T160-0638
1-(1-ethyl-1H-pyrazole-3-carbonyl)-4-({1-[(4-fluorophenyl)methyl]-5-methyl-1H-imidazol-2-yl}methyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T160-0638

Molecular Formula

C23H28FN5O (C23 H28 FN5 O)

Compound Name

1-(1-ethyl-1H-pyrazole-3-carbonyl)-4-({1-[(4-fluorophenyl)methyl]-5-methyl-1H-imidazol-2-yl}methyl)piperidine

IUPAC name

1-(1-ethyl-1H-pyrazole-3-carbonyl)-4-({1-[(4-fluorophenyl)methyl]-5-methyl-1H-imidazol-2-yl}methyl)piperidine

SMILES

CCn(cc1)nc1C(N1CCC(Cc2ncc(C)n2Cc(cc2)ccc2F)CC1)=O

InChI

InChI=1S/C23H28FN5O/c1-3-28-13-10-21(26-28)23(30)27-11-8-18(9-12-27)14-22-25-15-17(2)29(22)16-19-4-6-20(24)7-5-19/h4-7,10,13,15,18H,3,8-9,11-12,14,16H2,1-2H3

InChI Key

XRRQKDTZVKCBGU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31973212

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.51

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.037

Distribution Coefficient, logD

1.356

Water Solubility, LogSw

-2.77

Polar Surface Area

43.161

Acid Dissociation Constant (pKa)

23.06

Base Dissociation Constant (pKb)

9.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.48

T160-0638 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T160-0638 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T160-0638?
Check Price and Availability of T160-0638, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T160-0638 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T160-0638
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T160-0638
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T160-0638 available by request